Browsing Dissertations by Title
Now showing items 525-544 of 1044
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Integrative Complexity of Coastal Resources Management: Examining Tradeoffs Between Ecosystem Protection and Resource Use
(East Carolina University, 2018-07-20)The management dilemma of use versus protection is a complex issue, and like most complex issues, it does not lend itself to a simple or simplistic solution. This dissertation research examined the connection between ... -
Integrative multi-omic analyses identify novel biomarkers for recurrent stroke in participants from the Vitamin Intervention for Stroke Prevention (VISP) clinical trial
(East Carolina University, 2019-05-01)Background: Recurrent strokes are deadlier and more disabling than primary strokes and over 185,000 individuals in the US suffer a recurrent event each year. Current diagnostic and at-risk identification tools are inadequate ... -
Interaction of memantine with ethanol consumption and dopaminergic function in high ethanol preferring rats
(East Carolina University, 2009)N-methyl-D-aspartate (NMDA) receptor antagonists have been reported to decrease ethanol consumption in rodents, but these drugs often produce adverse side effects. Memantine is a neuroprotective and low-affinity, ... -
Interim Assessments as a Predictive Tool and Driver of Formative Assessment Practices to Improve Student Performance on State Assessments
(East Carolina University, 2019-07-08)The problem of practice on which this study focused was the establishment of interim assessments as a predictive tool and driver of formative assessment practices to improve student performance. The initial phase of ... -
The International Trade and Fishery Management of Spiny dogfish (Squalus Acanthias) in Light of CITES List Insertion : Alternative Management Strategies for the U.S. North Atlantic Stock
(East Carolina University, 2013)The spiny dogfish (Squalus acanthias) is a commercial shark species that was recently considered, unsuccessfully, for inclusion in trade-regulation lists due to international concern about its conservation status. The major ... -
The Interpretive Process of North Carolina Community College System Developmental Education Policy at Select Community Colleges
(East Carolina University, 2008-11)The purpose of this study was to examine the interpretive processes of administrators and staff at individual community colleges in the North Carolina system. The study examines how developmental education policy, established ... -
The intracellular proteolytic fragment of CD44 alters CD44 function in chondrocytes
(East Carolina University, 2010)CD44 is an adhesion molecule involved in several biological functions and the primary receptor for hyaluronan (HA). In cartilage, CD44 participates in the interplay between cells and the extracellular matrix to fine tune ... -
INTRINSIC EXERCISE CAPACITY ON HIND LIMB ARTERIAL LIGATION: DIFFERENTIAL IMPACT OF ACTIVE EXERCISE AND ANDROGEN SIGNALING ON POST-ISCHEMIC RECOVERY
(East Carolina University, 2018-12-21)Peripheral arterial disease (PAD) is a common disease that is frequently caused by atherosclerosis and associated thrombosis, leading to a decrease in the blood supply to the lower extremities. PAD has various treatment ... -
INTRODUCING TRANSLANGUAGING PRACTICES IN AN INTERNATIONAL ELEMENTARY SCHOOL: THE CRITICAL ROLE OF INSTRUCTIONAL ASSISTANTS.
(East Carolina University, 2023-04-21)Language is the vehicle through which we express ourselves and interact with the people and places around us. Language shapes our identity within the varied communities in which we belong. Translanguaging is a concept that ... -
INVESTIGATING MECHANISMS REGULATING MAMMALIAN SPERMATOGONIAL DIFFERENTIATION AND MEIOTIC INITIATION
(East Carolina University, 2022-06-27)Spermatogonia differentiation and meiotic initiation are complex processes essential for male fertility. Despite knowing for nearly 60 years that retinoic acid (RA) is instrumental for successful production of functional ... -
INVESTIGATING MECHANISMS REGULATING MAMMALIAN SPERMATOGONIAL DIFFERENTIATION AND MEIOTIC INITIATION
(East Carolina University, 2022-06-27)Spermatogonia differentiation and meiotic initiation are complex processes essential for male fertility. Despite knowing for nearly 60 years that retinoic acid (RA) is instrumental for successful production of functional ... -
Investigating Non-Tight Junction Functions of Claudin-7: Regulating Large Intestine Stem Cell Functions and Niche Maintenance, and Junctional Protein Nanoarchitecture
(East Carolina University, 2022-12-12)Edit this abstract. -
Investigating the genetic basis of aposematic coloration in poison frogs
(East Carolina University, 2023-11-29)Aposematic organisms rely on their conspicuous appearance to signal that they are defended and unpalatable. Such phenotypes are strongly tied to survival and reproduction. Aposematic colors and patterns are highly variable; ... -
An Investigation of Auditory and Visual Temporal Processing in Children with Reading Disorders
(East Carolina University, 2009)Several lines of research have revealed a relationship between reading disorders (RD) and auditory temporal processing deficits. That is, subtle, yet rapid changes within an acoustic message are more difficult for individuals ... -
Investigation of the Anatomical and Physiological Changes Following the Use of a Pedicled Buccal Fat Pad Graft During Primary Palatoplasty
(East Carolina University, 2019-07-19)Children with cleft palate typically undergo primary surgery between 6-12 months of age to close the cleft in the palate and create proper muscle function for elevation and retraction of the velum for speech. About one ... -
Investigation of the Zinc binding region of Prothymosin-alpha : A spectroscopic and thermodynamic approach to study metal binding in Intrinsically disordered proteins
(East Carolina University, 2014)The goal of this study is to provide a deeper insight into how metals bind intrinsically disordered proteins (IDPs) by taking zinc binding to prothymosin-alpha as a case study. The involvement of metals in several diseases ... -
Investigations into the roles of bacteroides fragilis thioredoxins during the oxidative stress response
(East Carolina University, 2011)The Gram-negative Bacteroides fragilis is the most frequently isolated bacterium from anaerobic infections. Native to the human intestinal tract, it serves a symbiotic role breaking down complex polysaccharides and ... -
The involvement of cap-independent mRNA translation in cell fate decisions
(East Carolina University, 2014)During cell stress many biochemical processes are shut down. For example, global mRNA translation initiation is inhibited due to the disruption of the cap-dependent mRNA recruitment mechanism. One specific example of ... -
Ion Traffic Across Cellular Membranes
(East Carolina University, 2010)The cell membrane protects the delicate internal machinery of the cell and hosts a complex transport system for ion exchange with the environment. Energy is continually expended to maintain a transmembrane electrical ... -
The iron response regulator Irr controls iron homoeostasis in Brucella
(East Carolina University, 2014)Members of the genus Brucella are small, Gram-negative intracellular bacterial pathogens that are capable of infecting a wide range of mammalian hosts including humans. Brucella primarily reside inside of host macrophages. ...