Browsing Dissertations by Author "Thomassen, Mary Jane"
-
The role of peroxisome proliferator-activated receptor-gamma in surfactant catabolism in the alveolar macrophage
Baker, Anna DeLane (East Carolina University, 2009)Pulmonary alveolar proteinosis (PAP) is a lung disease characterized by surfactant accumulation in the alveolar spaces and alveolar macrophages. Although PAP is rare, surfactant abnormalities occur in many lung diseases ... -
THE ROLE OF THE ALVEOLAR MACROPHAGE IN CARBON NANOTUBE ELICITED MURINE MODEL OF PULMONARY GRANULOMATOUS INFLAMMATION
McPeek, Matthew (East Carolina University, 2018-11-29)Pulmonary sarcoidosis is a debilitating inflammatory condition characterized by the presence of granulomatous lesions throughout the lung. Granulomas are a physiological response to inhaled antigens or particulate matter ...