Browsing Dissertations by Author "Yang, Li V"
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The Functional Roles of pH-sensing G protein-coupled receptors in Intestinal Inflammation
Sanderlin, Edward Joseph (East Carolina University, 2018-12-06)The inflammatory microenvironment in inflammatory bowel disease (IBD) is complex, replete with microbial byproducts, complement, leukocytes, and resulting inflammatory cytokines. Parallel to these microenvironmental factors ... -
THE PRO-INFLAMMATORY ROLE OF G-PROTEIN COUPLED RECEPTOR 4 IN AN ACIDIC MICROENVIRONMENT
Krewson, Elizabeth (East Carolina University, 2018-07-20)The endothelium of the microvascular system serves an ideal mediator between circulating blood and tissues in order to regulate systemic homeostasis. During vascular disease, the normal function and phenotype of endothelial ... -
The Tumor Suppressive Effects of T Cell Death-Associated Gene 8 in Blood Cancers
Justus, Calvin Richard (East Carolina University, 2017-03-16)In the early twentieth century Otto Warburg recognized a metabolic phenomenon that transpired in cancer cells, currently known as the Warburg Effect. Warburg discovered cancer cells favor glycolysis rather than oxidative ...