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RNA polymerase II CTD Evolutionary Diversity and Associated Protein Identification in Green and Red Algae
(East Carolina University, 2014)
In model eukaryotes, the C-terminal domain (CTD) of the largest subunit (RPB1) of DNA-dependent RNA polymerase II is composed of tandemly repeated heptads with the consensus sequence YSPTSPS. Both the core motif and tandem ...
The therapeutic potential of Rho GTPase intervention
(East Carolina University, 2013)
Small GTPases of the Rho family are well established regulators of critical cellular functions including cytoskeletal remodeling, motility, vesicle trafficking and cell cycle control. Additionally, aberrant signaling ...