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Development of Computational Tools and Resources for Cotton microRNA Analysis
(East Carolina University, 2014)
MicroRNAs (miRNAs) are an extensive class of small regulatory RNAs which regulate gene expression at the posttranscriptional levels. miRNAs target genes for mRNA cleavage or translation inhibition based on the complementary ...
RNA polymerase II CTD Evolutionary Diversity and Associated Protein Identification in Green and Red Algae
(East Carolina University, 2014)
In model eukaryotes, the C-terminal domain (CTD) of the largest subunit (RPB1) of DNA-dependent RNA polymerase II is composed of tandemly repeated heptads with the consensus sequence YSPTSPS. Both the core motif and tandem ...
Evaluating The Essential Functions Of The Replication Factor Mcm10 In Drosophila Melanogaster
(East Carolina University, 2015)
Often referred to as miraculous, life as we know depends not upon miracles but on a series of highly orchestrated and regulated biochemical processes collectively known as the cell cycle. It is through these series of ...
Rectifying Limitations On Species Delineation In Dusky Salamanders : Lineage Detection Using An Ecoregion-Drainage Sampling Regime
(East Carolina University, 2015)
The dusky salamanders (Desmognathus) constitute a large, species-rich group, and although a considerable body of literature exists on systematic relationships and adaptive trends, these issues have heretofore been approached ...
Fundamental and Applied Studies on Chromatographic Separation of Cold Drugs and Skincare Creams and Extraction of Salvia miltiorrhiza using Subcritical Water
(East Carolina University, 2014)
Subcritical water chromatography (SBWC) and subcritical water extraction (SBWE) are two green techniques that use subcritical water as the sole solvent for separations, thus eliminating the use of toxic and expensive organic ...
Fishing For The Evolutionary Bases Of Female Ornamentation
(East Carolina University, 2015)
Sexual dimorphism, or phenotypic differentiation of the sexes, is widespread amongst animals. It is understood mainly in the context of sexual selection, i.e. selection on mating success, with such selection typically ...
REPRODUCTIVE ISOLATION AND MIMETIC DIVERGENCE IN THE POISON FROG RANITOMEYA IMITATOR
(East Carolina University, 2014)
Understanding the process of speciation requires examination of various stages of its progress. This work focuses on the early stages of population divergence, where populations of a single species may show varying levels ...
DETECTION AND DISTRIBUTION OF THE AMPHIBIAN FUNGAL DISEASE CHYTRIDIOMYCOSIS IN PERUVIAN AMPHIBIANS
(East Carolina University, 2012)
Chytridiomycosis is an amphibian disease caused by the fungal pathogen Batrachochytrium dendrobatidis (Bd;Longcore et al. 1999). This disease has been identified by the Amphibian Conservation Action Plan as one of the main ...
HIGHER-LEVEL SYSTEMATICS OF THE MILLIPEDES (ARTHROPODA: MYRIAPODA: DIPLOPODA) EVALUATED USING TRANSCRIPTOMIC DATA, MITOCHONDRIAL GENOMICS, AND CLASSIFICATION ANALYSES
(East Carolina University, 2012)
Knowledge of deep level phylogenetic relationships within and between many animal groups is currently lacking. Past attempts to reconstruct these ancient evolutionary relationships once relied chiefly on morphological ...
The therapeutic potential of Rho GTPase intervention
(East Carolina University, 2013)
Small GTPases of the Rho family are well established regulators of critical cellular functions including cytoskeletal remodeling, motility, vesicle trafficking and cell cycle control. Additionally, aberrant signaling ...