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5'-AMP-Activated Protein Kinase and Eukaryotic Elongation Factor 2 Response to Resistance Exercise in Young Versus Old Men and Women
(East Carolina University, 2009)
It has been shown that skeletal muscle 5'-AMP-activated protein kinase (AMPK) phosphorylation and/or activity is more greatly elevated in response to resistance exercise or loading in aged rats, and that eukaryotic elongation ...
A sex-specific relationship between capillary density and anaerobic threshold
(East Carolina University, 2009-04)
Although both capillary density and peak oxygen consumption (VO2) improve with exercise training, it is difficult to find a relationship between these two measures. It has been suggested that peak VO2 may be more related ...
Intramuscular Lipid Metabolism, Insulin Action and Obesity
(East Carolina University, 2009-01)
With the increasing prevalence of obesity, research has focused on the molecular mechanism(s) linking obesity and skeletal muscle insulin resistance. Metabolic alterations within muscle, such as changes in the cellular ...
Effects of Parental Obesity on Fat Metabolism During Submaximal Exercise in Children
(East Carolina University, 2009)
The aim of the present study was to compare fat metabolism during submaximal exercise in children with a morbidly obese parent - (COP) (BMI [greater than or equal to] 40 kg/m²) to children with relatively lean parents - ...
The Intensive Diet and Exercise for Arthritis (IDEA) trial: design and rationale
(East Carolina University, 2009-07-28)
Background: Obesity is the most modifiable risk factor, and dietary induced weight loss potentially the best nonpharmacologic intervention to prevent or to slow osteoarthritis (OA) disease progression. We are currently ...
Regulation of GLUT4 expression in denervated skeletal muscle
(East Carolina University, 2009-03)
Denervation by sciatic nerve resection causes decreased muscle glucose transporter 4 (GLUT4) expression, but little is known about the signaling events that cause this decrease. Experiments were designed to test the ...
Increased Secretion and Expression of Myostatin in Skeletal Muscle From Extremely Obese Women
(East Carolina University, 2009-01)
OBJECTIVE- Obesity is associated with endocrine abnormalities that predict the progression of insulin resistance to type 2 diabetes. Because skeletal muscle has been shown to secrete proteins that could be used as biomarkers, ...
Does Minimally Invasive Robotic Surgical Treatment Alter Exercise Tolerance in Patients with Atrial Fibrillation and Mitral Regurgitation at Seven to Eleven Weeks Post-Operative?
(East Carolina University, 2009)
In the current study, we examined if exercise tolerance was going to be reduced in atrial fibrillation and mitral valve regurgitation patients post a minimally invasive surgery seven to eleven weeks when compared to ...
Physical Activity, Academic Performance, and Physical Self-Description in Adolescent Females
(East Carolina University, 2009)
Despite the many health benefits of being physically active, nearly a quarter of U.S. adults and adolescents report no participation in leisure-time physical activity. It is recommended that children and adolescents ...
Chronic low-frequency rTMS of primary motor cortex diminishes exercise training-induced gains in maximal voluntary force in humans
(East Carolina University, 2009)
Although there is consensus that the central nervous system mediates the increases in maximal voluntary force (maximal voluntary contraction, MVC) produced by resistance exercise, the involvement of the primary motor cortex ...