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    AuthorBattaglia, Gina (1)Choplin, Eric Seneca (1)Fisher-Wellman, Kelsey H. (1)Lark, Daniel Stephen (1)Mayo, William Joseph (1)Subject
    Physiology (5)
    Skeletal muscle (5)
    Biology, Physiology (4)Mitochondria (4)Kinesiology (2)Aging (1)AMPK (1)Apoptosis (1)Biochemistry (1)Bioenergetics (1)... View MoreDate Issued2013 (2)2011 (1)2012 (1)2014 (1)Has File(s)
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    Cleaved Caspase-3 Response to Acute Resistance Exercise in Young and Old Men and Women : Relationship to Muscle Glycogen Content and 5'-AMP-Activated Protein Kinase (AMPK) Activity 

    Choplin, Eric Seneca (East Carolina University, 2011)
    In addition to suppressing protein synthesis and activating protein degradation in skeletal muscle and other cell types, 5'-AMP-activated protein kinase (AMPK) is known to stimulate nuclear apoptosis in non-muscle cells ...
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    NOVEL MECHANISMS GOVERNING SKELETAL MUSCLE MITOCHONDRIAL BIOENERGETICS : OXPHOS EFFICIENCY AND cAMP/PKA SIGNALING 

    Lark, Daniel Stephen (East Carolina University, 2014)
    Understanding the regulation of cellular metabolism is paramount to treating the growing prevalence of metabolic disease worldwide. In cellular metabolism, mitochondrial oxidative phosphorylation (OXPHOS) plays a key role ...
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    SKELETAL MUSCLE METABOLIC FLEXIBILITY IMPAIRMENTS IN RESPONSE TO LIPID WITH OBESITY : EFFECT OF EXERCISE TRAINING 

    Battaglia, Gina (East Carolina University, 2012)
    Obese individuals exhibit skeletal muscle metabolic inflexibility by failing to increase fat oxidation and genes linked with mitochondrial biogenesis in response to a high-fat diet (HFD) and lipid incubation in cell culture. ...
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    The effects of statins on mitochondrial function 

    Mayo, William Joseph (East Carolina University, 2013)
    Statins, or 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors, are among the most commonly prescribed medications in the United States. They are commonly used to treat hypercholesterolemia, a condition ...
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    ESTABLISHMENT OF THE PYRUVATE DEHYDROGENASE COMPLEX AS A CENTRAL REGULATOR OF MITOCHONDRIAL REDOX WITHIN SKELETAL MUSCLE 

    Fisher-Wellman, Kelsey H. (East Carolina University, 2013)
    Once regarded as "byproducts" of aerobic metabolism, the production of superoxide/H₂O₂ is now understood to be a highly specialized and extensively regulated process responsible for exerting control over a vast number of ...

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