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Now showing items 31-40 of 40
Muscle Work Discrepancy during Incline and Decline Running at Three Speeds
(East Carolina University, 2009)
Introduction: Previous research has explored muscle function during gait and this work has shown that more positive mechanical muscle work is produced in gait tasks that primarily raise the center of mass (incline gait ...
Gender Differences in Aerobic and Work Capacity During Plantar Flexion Exercise
(East Carolina University, 2009)
Maximal oxygen consumption (VO2max) is lower in females compared to males during traditional whole body, systemic exercise. These differences in VO2max between men and women are still present even after correcting for ...
Effect of Acute Exercise or Fasting on Mitochondrial Function and High Fat Diet-Induced Insulin Resistance
(East Carolina University, 2009)
A high-fat diet leads to an accumulation of lipid in skeletal muscle, and the development of both mitochondrial dysfunction and insulin resistance. Recently, our lab reported that lipid overload leads to elevated ...
Muscles do more positive than negative work in human locomotion
(East Carolina University, 2007-10)
Muscle work during level walking and ascent and descent ramp and stairway walking was assessed in order to explore the proposition that muscles perform more positive than negative work during these locomotion tasks. Thirty ...
How do low horizontal forces produce disproportionately high torques in human locomotion?
(East Carolina University, 2008)
Although horizontal ground forces are only ~15% of vertical forces, they account for 47% and 33% of the metabolic cost in walking and running. To explain these disproportionately high metabolic costs we hypothesized that ...
Effect of Duodenal-Jejunal Bypass on Skeletal Muscle Insulin Signaling in Goto-Kakizaki Rats
(East Carolina University, 2009)
Gastric bypass surgery (RYGBP) for the treatment of obesity has proven to clinically reverse type 2 diabetes mellitus. RYGBP involves both gastric reduction and bypass of the proximal small intestine. Duodenal-Jejunal ...
Review of microdialysis in brain tumors, from concept to application: First Annual Carolyn Frye-Halloran Symposium
(East Carolina University, 2004-01)
In individuals with brain tumors, pharmacodynamic and pharmacokinetic studies of therapeutic agents have historically used analyses of drug concentrations in serum or cerebrospinal fluid, which unfortunately do not necessarily ...
Assessing Children's Physical Activity in Their Homes: The Observational System for Recording Physical Activity in Children-Home
(East Carolina University, 2009)
The present study describes the development and pilot testing of the Observation System for Recording Physical Activity in Children-Home version. This system was developed to document physical activity and related physical ...
AMP-activated protein kinase response to contractions and treatment with the AMPK activator AICAR in young adult and old skeletal muscle
(East Carolina University, 2009-05-01)
One characteristic of aging skeletal muscle is a decline in mitochondrial function. Activation of AMP-activated protein kinase (AMPK)occurs in response to an increased AMP/ATP ratio,which is one potential result of ...
Teager-Kaiser Operator improves the accuracy of EMG onset detection independent of signal-to-noise ratio
(East Carolina University, 2008)
A temporal analysis of electromyographic (EMG) activity has widely been used for non-invasive study of muscle activation patterns. Such an analysis requires robust methods to accurately detect EMG onset. We examined whether ...