Browsing Microbiology and Immunology by Author "Bellaire, Bryan H."
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Opsonized Virulent Brucella abortus Replicates within Nonacidic, Endoplasmic Reticulum-Negative, LAMP-1-Positive Phagosomes in Human Monocytes
Bellaire, Bryan H.; Roop, R. Martin II; Cardelli, James A. (East Carolina University, 2005-06)Cells in the Brucella spp. are intracellular pathogens that survive and replicate within host monocytes. Brucella maintains persistent infections in animals despite the production of high levels of anti-Brucellaspecific ... -
Production of the Siderophore 2,3-Dihydroxybenzoic Acid Is Required for Wild-Type Growth of Brucella abortus in the Presence of Erythritol under Low-Iron Conditions In Vitro
Bellaire, Bryan H.; Elzer, Philip H.; Baldwin, Cynthia L.; Roop, R. Martin II (East Carolina University, 2003-05)Production of the siderophore 2,3-dihyroxybenzoic acid (2,3-DHBA) is required for the wild-type virulence of Brucella abortus in cattle. A possible explanation for this requirement was uncovered when it was determined that ... -
RecA and RadA Proteins of Brucella abortus Do Not Perform Overlapping Protective DNA Repair Functions following Oxidative Burst
Roux, Christelle M.; Booth, Natha J.; Bellaire, Bryan H.; Gee, Jason M.; Roop, R. Martin II; Kovach, Michael E.; Tsolis, Renee M.; Elzer, Philip H.; Ennis, Don G. (East Carolina University, 2006-07)Very little is known about the role of DNA repair networks in Brucella abortus and its role in pathogenesis. We investigated the roles of RecA protein, DNA repair, and SOS regulation in B. abortus. While recA mutants in ...