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The Manganese Transporter MntH Is a Critical Virulence Determinant for Brucella abortus 2308 in Experimentally Infected Mice
(East Carolina University, 2009-08)
The gene designated BAB1_1460 in the Brucella abortus 2308 genome sequence is predicted to encode the manganese transporter MntH. Phenotypic analysis of an isogenic mntH mutant indicates that MntH is the sole high-affinity ...
A Müllerian mimicry ring in Appalachian millipedes
(East Carolina University, 2009-06-16)
Few biological phenomena provide such an elegant and straightforward
example of evolution by natural selection as color mimicry among unrelated organisms. By mimicking the appearance of a heavily defended aposematic ...
Amazonian Amphibian Diversity Is Primarily Derived from Late Miocene Andean Lineages
(East Carolina University, 2009-03)
The Neotropics contains half of remaining rainforests and Earth’s largest reservoir of amphibian biodiversity. However, determinants of Neotropical biodiversity (i.e., vicariance, dispersals, extinctions, and radiations) ...
Are algal genes in nonphotosynthetic protists evidence of historical plastid endosymbioses?
(East Carolina University, 2009)
Background: How photosynthetic organelles, or plastids, were acquired by diverse eukaryotes is among the most hotly debated topics in broad scale eukaryotic evolution. The history of plastid endosymbioses commonly is ...
RDX Induces Aberrant Expression of MicroRNAs in Mouse Brain and Liver
(East Carolina University, 2009-02)
Background: Although microRNAs (miRNAs) have been found to play an important role in many biological and metabolic processes, their functions in animal response to environmental toxicant exposure are largely unknown. ...
RDX and miRNA Expression: Zhang and Pan Respond
(East Carolina University, 2009-03)
Pleistocene glacial refugia across the Appalachian Mountains and coastal plain in the millipede genus Narceus: Evidence from population genetic, phylogeographic, and paleoclimatic data
(East Carolina University, 2009-01-30)
Background: Species that are widespread throughout historically glaciated and currently nonglaciated areas provide excellent opportunities to investigate the role of Pleistocene climatic change on the distribution of North ...
Analyses of domains and domain fusions in human proto-oncogenes
(East Carolina University, 2009-03-17)
Background: Understanding the constituent domains of oncogenes, their origins and their fusions may shed new light about the initiation and the development of cancers. Results: We have developed a computational pipeline ...
Ecological effects of rising sea level on shorezone
(East Carolina University, 2009)
This study examines the ecological effects of sea-level rise on shorezone in the Neuse River estuary and western Pamlico Sound, NC. Shorezone is defined here in an ecohydrological context as the area of wetland that extends ...
Tactical reproductive parasitism via larval cannibalism in Peruvian poison frogs
(East Carolina University, 2009-04-23)
We report an unusual example of reproductive parasitism in amphibians. Dendrobates variabi- lis, an Amazonian poison frog, oviposits at the surface of the water in small pools in plants and deposits tadpoles within the ...