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Versican Expression during Synovial Joint Morphogenesis
(East Carolina University, 2007-09)
The extracellular matrix (ECM) plays a critical role in governing cell behavior and phenotype during limb skeletogenesis. Chondroitin sulfate proteoglycans (Cspgs) are highly expressed in the ECM of precartilage mesenchymal ...
Did an ancient chlamydial endosymbiosis facilitate the establishment of primary plastids?
(East Carolina University, 2007-06)
Background: Ancient endosymbioses are responsible for the origins of mitochondria and plastids, and they contribute to the divergence of several major eukaryotic groups. Although chlamydiae, a group of obligate intracellular ...
Adaptive evolution of genes underlying schizophrenia
(East Carolina University, 2007-11-22)
Schizophrenia poses an evolutionary-genetic paradox because it exhibits strongly negative fitness effects and high heritability, yet it persists at a prevalence of approximately 1% across all human cultures. Recent theory ...
Gamma Protocadherin Expression in the Embryonic Chick Nervous System
(East Carolina University, 2007)
Protocadherin gamma (pcdh-gamma) family expression was examined in the embryonic chick central nervous system by in situ hybridization. Transcripts were visualized in discrete regions of fore-, mid-, and hindbrain at stages ...