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  • NMR characterizations of an amyloidogenic conformational ensemble of the PI3K SH3 domain 

    Ahn, Hee-Chul; Le, Yen T. H.; Nagchowdhuri, Partha S.; Derose, Eugene F.; Putnam-Evans, Cindy; London, Robert E.; Markley, John L.; Lim, Kwang Hun (East Carolina University, 2006-11)
    Amyloid formation is associated with structural changes of native polypeptides to monomeric intermediate states and their self-assembly into insoluble aggregates. Characterizations of the amyloidogenic intermediate state ...