Browsing Other Campus Research by Title
Now showing items 362-381 of 1103
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EPG5-related Vici syndrome: a paradigm of neurodevelopmental disorders with defective autophagy
(2016)Vici syndrome is a progressive neurodevelopmental multisystem disorder due to recessive mutations in the key autophagy gene EPG5. We report genetic, clinical, neuroradiological, and neuropathological features of 50 children ... -
EphrinA1-Fc attenuates myocardial ischemia/ reperfusion injury in mice
(2017-12-13)EphrinA1, a membrane-bound receptor tyrosine kinase ligand expressed in healthy car- diomyocytes, is lost in injured cells following myocardial infarction. Previously, we have reported that a single intramyocardial injection ... -
Epigenetic re-wiring of breast cancer by pharmacological targeting of C-terminal binding protein
(2019-08-08)The C-terminal binding protein (CtBP) is an NADH-dependent dimeric family of nuclear proteins that scaffold interactions between transcriptional regulators and chromatin-modifying complexes. Its association with poor ... -
Epigenome-Wide Analyses Identify Two Novel Associations With Recurrent Stroke in the Vitamin Intervention for Stroke Prevention Clinical Trial Citation metadata
(2018-09-06)DNA methylation, a well-characterized epigenetic modification that is influenced by both environment and genetic variation, has previously been implicated in a number of complex diseases, including cardiovascular disease ... -
Erratum to: Unity in defence: honeybee workers exhibit conserved molecular responses to diverse pathogens
(2017-03-23)Erratum After the publication of this work [1] it was noticed that there was a typesetting error in figure 5 where two add- itional red lines were added in the sections “gene expres- sion profiles” and “transformed gene ... -
The errors of individualistic public health interventions: Denial of treatment to obese persons: Comment on “Denial of treatment to obese patients—the wrong policy on personal responsibility for health”
(2013-09-28)I agree entirely with Nir Eyal’s perspective that denying treatment to obese patients is morally wrong. However, the reasons for this belief differ in some ways from Eyal’s analysis. In this commentary, I will try to explain ... -
Esophageal perforation secondary to malignant gastric outlet obstruction: a case report
(2019-02-19)Background Esophageal perforation is a rare presenting sign of gastric cancer. To date, only nine case reports of this phenomenon have been previously published. Case presentation Esophageal perforation was diagnosed ... -
Essential role of proteasomes in maintaining self-renewal in neural progenitor cells
(2016-01-25)Protein turnover and homeostasis are regulated by the proteasomal system, which is critical for cell function and viability. Pluripotency of stem cells also relies on normal proteasomal activity that mitigates senescent ... -
Establishment of the Coast Range ophiolite microbial observatory (CROMO): Drilling objectives and preliminary outcomes
(2013-11-05)Abstract. This project aimed to establish a subsurface microbial observatory in ultramafic rocks, by drilling into an actively serpentinizing peridotite body, characterizing cored rocks, and outfitting the boreholes for a ... -
Estimating coastal lagoon tidal flooding and repletion with multidate ASTER thermal imagery
(2012-10-18)Coastal lagoons mix inflowing freshwater and tidal marine waters in complex spatial patterns. This project sought to detect and measure temperature and spatial variability of flood tides for a constricted coastal lagoon ... -
Estimating internal consistency using Bayesian methods
(2011)Bayesian internal consistency and its Bayesian credible interval (BCI) are developed and Bayesian internal consistency and its percentile and normal theory based BCIs were investigated in a simulation study. Results indicate ... -
Estrogen Regulates the Satellite Cell Compartment in Females
(2019-07-09)Skeletal muscle mass, strength, and regenerative capacity decline with age, with many measures showing a greater deterioration in females around the time estrogen levels decrease at menopause. Here, we show that estrogen ... -
Ethnic differences in DNA methyltransferases expression in patients with systemic lupus erythematosus
(2013-10-09)Systemic lupus erythematous (SLE) is a systemic autoimmune inflammatory disease with both genetic and epigenetic etiologies. Evidence suggests that deregulation of specific genes through epigenetic mechanisms may be a ... -
An ethnographic exploration of a student subculture of sustained civic engagement
(2011-09)The purpose of this study is to describe how students understand their own participation in civic engagement activities, particularly as members of a supportive community. Research questions include: How do students ... -
Evaluating Combinations of Sentinel-2 Data and Machine-Learning Algorithms for Mangrove Mapping in West Africa
(2019-12-06)Creating a national baseline for natural resources, such as mangrove forests, and monitoring them regularly often requires a consistent and robust methodology. With freely available satellite data archives and cloud computing ... -
Evaluating Multipulse Integration as a Neural-Health Correlate in Human Cochlear-Implant Users: Relationship to Psychometric Functions for Detection
(2017-01)In electrical hearing, multipulse integration (MPI) describes the rate at which detection threshold decreases with increasing stimulation rate in a fixed-duration pulse train. In human subjects, MPI has been shown to be ... -
Evaluating the Cost of Collection, Processing, and Application of Face Masks in Hot-Mix Asphalt (HMA) Pavements
(2022)Human activities significantly contribution to the yearly generated plastic wastes. Moreover, the enormous increase in face masks and face shields caused by the emergence of the COVID-19 pandemic has doubled the generated ... -
Evaluating the Sustainability of Heritage Tourism and Historic Preservation in New Bern, North Carolina
(East Carolina University, 2010)After nearly a half century of suburbanization, economic development specialists and urban planners have begun to appreciate the unique aesthetic and heritage landscapes of underutilized downtown areas as potential geographic ... -
Evaluation of Methicillin-Resistant Staphylococcus aureus Carriage and High Livestock Production Areas in North Carolina through Active Case Finding at a Tertiary Care Hospital
(2019-09-14): Recent reports from the Netherlands document the emergence of novel multilocus sequence typing (MLST) types (e.g., ST-398) of methicillin-resistant Staphylococcus aureus (MRSA) in livestock, particularly swine. In ... -
Evaluation of Social Media Use by Emergency Medicine Residents and Faculty
(2015-09)Introduction Clinicians and residency programs are increasing their use of social media (SM) websites for educational and promotional uses, yet little is known about the use of these sites by residents and faculty. The ...