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Effectiveness of a Total Meal Replacement Program (OPTIFAST Program) on Weight Loss: Results from the OPTIWIN Study
(2018-11-13)
Objective: The aim of this study was to test the effectiveness of the OPTIFAST program (OP), a total meal replacement dietary intervention, compared with a food-based (FB) dietary plan for weight loss. Methods: Participants ...
Diversity in warning coloration: selective paradox or the norm?
(2018-08-27)
Aposematic theory has historically predicted that predators should select for warning signals to converge on a single form, as a result of frequency‐dependent learning. However, widespread variation in warning signals is ...
Factors Associated with Discharge to a Skilled Nursing Facility after Transcatheter Aortic Valve Replacement Surgery
(2018-12-28)
An assumption regarding transcatheter aortic valve replacement (TAVR), a minimally invasive procedure for treating aortic stenosis, is that patients remain at, or near baseline and soon return to their presurgical home to ...
Therapeutic Targeting of mTOR in T-Cell Acute Lymphoblastic Leukemia: An Update
(2018-06-26)
T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive blood malignancy that arises from the clonal expansion of transformed T-cell precursors. Although T-ALL prognosis has significantly improved due to the development ...
Integrated transcriptome, small RNA and degradome sequencing approaches provide insights into Ascochyta blight resistance in chickpea
(2018-10-16)
Ascochyta blight (AB) is one of the major biotic stresses known to limit the chickpea production worldwide. To dissect the complex mechanisms of AB resistance in chickpea, three approaches, namely, transcriptome, small RNA ...
Top-down pulses reduce prey population sizes and persistence
(2018-06-19)
Resource pulses are well documented and have important consequences for population dynamics relative to continuous inputs. However, pulses of top-down factors (e.g. predation) are less explored and appreciated in the ...
The state of the science of nurse work environments in the United States: A systematic review
(2018-04-16)
A healthy nurse work environment is a workplace that is safe, empowering, and satisfying. Many research studies were conducted on nurse work environments in the last decade; however, it lacks an overview of these research ...
The Multifunctional Protein BAG3: A Novel Therapeutic Target in Cardiovascular Disease
(2018-02-26)
The B-cell lymphoma 2–associated anthanogene (BAG3) protein is expressed most prominently in the heart, the skeletal muscle, and in many forms of cancer. In the heart, it serves as a co-chaperone with heat shock proteins ...
The National Clinical Assessment Tool for Medical Students in the Emergency Department (NCAT-EM)
(2018-01)
Introduction: Clinical assessment of medical students in emergency medicine (EM) clerkships is
a highly variable process that presents unique challenges and opportunities. Currently, clerkship directors use institution-specific ...
Glaucomatous optic disc changes despite normal baseline intraocular pressure in a child
(2018-12-14)
Purpose:
We describe a case of normal tension glaucoma in the setting of sickle cell disease in a 9-year-old patient with a five-year follow up.
Observations:
A 9-year-old male patient with a history of sickle cell ...