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Now showing items 11-20 of 159
A Clostridium difficile-Specific, Gel-Forming Protein Required for Optimal Spore Germination
(2017-01-17)
Clostridium difficile is a Gram-positive spore-forming obligate anaerobe that is a leading cause of antibiotic-associated diarrhea worldwide. In order for C. difficile to initiate infection, its aerotolerant spore form ...
A novel TCF7L2 type 2 diabetes SNP identified from fine mapping in African American women
(2017-03-02)
SNP rs7903146 in the Wnt pathway’s TCF7L2 gene is the variant most significantly associ- ated with type 2 diabetes to date, with associations observed across diverse populations. We sought to determine whether variants in ...
“Their Packaging Has Always Been Like a Power”: A Qualitative Study of U.S. Smokers’ Perceptions of Cigarette Pack Visual Design Features to Inform Product Regulation
(2017-10-17)
Cigarette packaging matters to consumer behavior. However, it is less clear which changes to packaging design would be salient for adult smokers. Such information is critically important to regulators in the United States ...
A Proposed Set of Metrics to Reduce Patient Safety Risk From Within the Anatomic Pathology Laboratory
(2017-05)
Background: Anatomic pathology laboratory workflow consists of 3 major specimen handling processes. Among the workflow are preanalytic, analytic, and postanalytic phases that contain multistep subprocesses with great impact ...
a single-institution analysis of 126 Patients Treated with stereotactic radiosurgery for Brain Metastases
(2017-05-12)
Background: The objective of this study was to report our institutional experience with Gamma Knife® Radiosurgery (GKRS) in the treatment of patients with brain metastases.
Methods: Retrospectively collected demographic ...
EphrinA1-Fc attenuates myocardial ischemia/ reperfusion injury in mice
(2017-12-13)
EphrinA1, a membrane-bound receptor tyrosine kinase ligand expressed in healthy car- diomyocytes, is lost in injured cells following myocardial infarction. Previously, we have reported that a single intramyocardial injection ...
Functional imaging of cognition in an old-old population: A case for portable functional near-infrared spectroscopy
(2017-10-12)
In this study, functional near-infrared spectroscopy (fNIRS) was used to record brain activa- tion during cognitive testing in older individuals (88±6yo; N = 19) living in residential care communities. This population, ...
Gemella Species Bacteremia and Stroke in an Elderly Patient with Respiratory Tract Infection
(2017-01-02)
Gemella species are part of normal human flora. They are rarely associated with infections. As opportunistic pathogens, they can cause life-threatening infection in individuals with risk factors. We present an unusual case ...
It’s not what you expect: feedback negativity is independent of reward expectation and affective responsivity in a non-probabilistic task
(2017-03)
ERP studies commonly utilize gambling-based reinforcement tasks to elicit feedback negativity (FN) responses. This study used a pattern learning task in order to limit gambling-related fallacious reasoning and possible ...
Impaired contractile function of the supraspinatus in the acute period following a rotator cuff tear
(2017-11-09)
Background: Rotator cuff (RTC) tears are a common clinical problem resulting in adverse changes to the muscle, but there is limited information comparing histopathology to contractile function. This study assessed supraspinatus ...