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Now showing items 51-60 of 101
Examining signals of trust in criminal markets online
(2016-09-14)
This study examines the signals of trust in stolen data advertisements by analysing the structural and situational factors that influence the type of feedback sellers receive. Specifically, this article explores the factors ...
Essential role of proteasomes in maintaining self-renewal in neural progenitor cells
(2016-01-25)
Protein turnover and homeostasis are regulated by the proteasomal system, which is critical for
cell function and viability. Pluripotency of stem cells also relies on normal proteasomal activity that mitigates senescent ...
Failure patterns and survival outcomes in triple negative breast cancer (TNBC): a 15 year comparison of 448 non-Hispanic black and white women
(2016-06-17)
Purpose: Triple negative breast cancer (TNBC) is a distinct subtype of breast cancer with unique pathologic, molecular and clinical behavior. It occurs more frequently in young blacks and has been reported to have a shorter ...
Genome-wide association study identifies multiple susceptibility loci for craniofacial microsomia
(2016-02-08)
Craniofacial microsomia (CFM) is a rare congenital anomaly that involves immature derivatives from the first and second pharyngeal arches. The genetic pathogenesis of CFM is still unclear. Here we interrogate 0.9 million ...
Quantitative assessment of image motion blur in diffraction images of moving biological cells
(2016-02)
Motion blur (MB) presents a significant challenge for obtaining high-contrast image data from biological cells with a polarization diffraction imaging flow cytometry (p-DIFC) method. A new p-DIFC experimental system has ...
Pioglitazone Enhances the Beneficial Effects of Glucocorticoids in Experimental Nephrotic Syndrome
(2016-05)
Glucocorticoids are the primary therapy for nephrotic syndrome (NS), but have serious side effects and are ineffective in ~20-50% of patients. Thiazolidinediones have recently been suggested to be renoprotective, and to ...
Murine mesothelin: characterization, expression, and inhibition of tumor growth in a murine model of pancreatic cancer
(2016)
Background: Mesothelin has attracted much interest as a tumor specific antigen; it has been reported to promote
tumor development and to be a good target for cancer treatment. Most studies to date have used human
mesothelin ...
The Bee Microbiome: Impact on Bee Health and Model for Evolution and Ecology of Host-Microbe Interactions
(2016)
As pollinators, bees are cornerstones for terrestrial ecosystem stability and key components in agricultural productivity. All animals, including bees, are associated with a diverse community of microbes, commonly referred ...