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The errors of individualistic public health interventions: Denial of treatment to obese persons: Comment on “Denial of treatment to obese patients—the wrong policy on personal responsibility for health”
(2013-09-28)
I agree entirely with Nir Eyal’s perspective that denying treatment to obese patients is morally wrong. However, the reasons for this belief differ in some ways from Eyal’s analysis. In this commentary, I will try to explain ...
Monitoring Rice Phenology Based on Backscattering Characteristics of Multi-Temporal RADARSAT-2 Datasets
(2018-02-23)
Accurate estimation and monitoring of rice phenology is necessary for the management and yield prediction of rice. The radar backscattering coefficient, one of the most direct and accessible parameters has been proved to ...
Vascular tissue contractility changes following late gestational exposure to multi-walled carbon nanotubes or their dispersing vehicle in Sprague Dawley rats
(2014-04-20)
Multi-walled carbon nanotubes (MWCNTs) are increasingly used in industry and in nanomedicine raising safety concerns, especially during unique life-stages such as pregnancy. We hypothesized that MWCNT exposure during ...
miRNA-23a/27a attenuates muscle atrophy and renal fibrosis through muscle-kidney crosstalk
(2018-03-26)
Background The treatment of muscle wasting is accompanied by benefits in other organs, possibly resulting from muscle– organ crosstalk. However, how the muscle communicates with these organs is less understood. Two microRNAs ...
A double-blind, randomized, multicenter phase 2 study of prasugrel versus placebo in adult patients with sickle cell disease
(2013-02)
Background
Platelet activation has been implicated in the pathogenesis of sickle cell disease (SCD) suggesting antiplatelet agents may be therapeutic. To evaluate the safety of prasugrel, a thienopyridine antiplatelet ...
VASP activation via the Gα13/RhoA/PKA pathway mediates cucurbitacin-B-induced actin aggregation and cofilin-actin rod formation
(2014-04-01)
Cucurbitacin B (CuB), a potent antineoplastic agent of cucurbitacin triterpenoids, induces rapid disruption of actin cytoskeleton and aberrant cell cycle inhibiting carcinogenesis. However, the underlying molecular mechanism ...
WalkMore: A randomized controlled trial of pedometer-based interventions differing on intensity messages
(2014-02-15)
Pedometer-based programs have elicited increased walking behaviors associated with improvements in blood pressure in sedentary/low active postmenopausal women, a population at increased risk of cardiovascular disease. Such ...
Using the stable carbon and nitrogen isotope compositions of vervet monkeys (Chlorocebus pygerythrus) to examine questions in ethnoprimatology
(2014-07-10)
This study seeks to understand how humans impact the dietary patterns of eight free-ranging vervet monkey (Chlorocebus pygerythrus) groups in South Africa using stable isotope analysis. Vervets are omnivores that exploit ...
Mitigation Effect of Waste Glass Powders on Alkali–Silica Reaction (ASR) Expansion in Cementitious Composite
(2018-11-20)
The effects of different contents and particle sizes of waste glass powder on alkali–silica reaction (ASR) expansion of cementitious composite bar were investigated in this study. Waste glass powder with particle size less ...
Methods for assessing mitochondrial function in diabetes
(2013-03-14)
A growing body of research is investigating the potential contribution of mitochondrial function to the etiology of type 2 diabetes. Numerous in vitro, in situ, and in vivo methodologies are available to examine various ...