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Analysis of the B-RAFV600E mutation in cutaneous melanoma patients with occupational sun exposure
Sun-exposure is one of the risk factors associated with the development of a cutaneous neoplasm. In melanoma, the Ras-Raf-MEK-ERK (MAPK) signaling pathway is constitutively activated through multiple mechanisms, including ...
Roles of neutrophil gelatinase-associated lipocalin (NGAL) in human cancer
Cancer remains one of the major cause of death in the Western world. Although, it has been demonstrated that new therapies can improve the outcome of cancer patients, still many patients relapse after treatment. Therefore, ...