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Is the genetic landscape of the deep subsurface biosphere affected by viruses?
(2011-11-09)
Viruses are powerful manipulators of microbial diversity, biogeochemistry, and evolution in the marine environment. Viruses can directly influence the genetic capabilities and the fitness of their hosts through the use of ...
Conspecific brood parasitism in the tropics: An experimental investigation of host responses in common moorhens and American purple gallinules
(2011-08-03)
Species occupying a broad latitudinal range may show greater phenotypic plasticity in behavior than species with smaller ranges or more specific habitat requirements. This study investigates for the first time the occurrence ...
A multi-sensor approach to examining the distribution of total suspended matter (TSM) in the Albemarle-Pamlico Estuarine System, NC, USA
(2011)
For many coastal waters, total suspended matter (TSM) plays a major role in key biological, chemical and geological processes. Effective mapping and monitoring technologies for TSM are therefore needed to support research ...
Diet-induced muscle insulin resistance is associated with extracellular matrix remodeling and interaction with integrin α<inf>2</inf>β <inf>1</inf>in mice
(2011)
OBJECTIVE:
The hypothesis that high-fat (HF) feeding causes skeletal muscle extracellular matrix (ECM) remodeling in C57BL/6J mice and that this remodeling contributes to diet-induced muscle insulin resistance (IR) through ...
Direct inhibition of RNAse T2 expression by the HTLV-1 viral protein Tax
(2011-08-18)
Adult T-cell leukemia (ATL) is one of the primary diseases caused by Human T-cell Leukemia Virus type 1 (HTLV-1) infection. The virally-encoded Tax protein is believed to initiate early events in the development of this ...
Divergent roles of superoxide and nitric oxide in liver ischemia and reperfusion injury
(2011)
Liver ischemia and reperfusion-induced injury is a major clinical complication associated with hemorrhagic or endotoxin shock and thermal injury as well as liver transplantation and resectional surgery. Data obtained from ...
Strategies to improve palatability and increase consumption intentions for momordica charantia (bitter melon): A vegetable commonly used for diabetes management
(2011-07-28)
Background Although beneficial to health, dietary phytonutrients are bitter, acid and/or astringent in taste and therefore reduce consumer choice and acceptance during food selection. Momordica charantia, commonly known ...
Is there a metabolic program in the skeletal muscle of obese individuals?
(2011-04-26)
Severe obesity (BMI ≥ 40 kg/m2) is associated with multiple defects in skeletal muscle which contribute to insulin resistance and a reduction in fatty acid oxidation (FAO) in this tissue. These metabolic derangements are ...
Experimental design and statistical rigor in phylogenomics of horizontal and endosymbiotic gene transfer
(2011-09-16)
A growing number of phylogenomic investigations from diverse eukaryotes are examining conflicts among gene trees as evidence of horizontal gene transfer. If multiple foreign genes from the same eukaryotic lineage are found ...
From imitation to innovation: A study of China's drug R&D and relevant national policies
(2011)
Research & Development (R&D) plays an increasingly important role in China's pharmaceutical industry. To gain a competitive edge in the global pharmaceutical market, the current national strategy of China forcefully pushes ...