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Now showing items 1446-1465 of 2046
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PI3K activation is associated with intracellular sodium/iodide symporter protein expression in breast cancer
(East Carolina University, 2007-07-25)Background: The sodium/iodide symporter (NIS) is a membrane glycoprotein mediating active iodide uptake in the thyroid gland and is the molecular basis for radioiodide imaging and therapeutic ablation of thyroid carcinomas. ... -
PI3K mediated activation of GSK‑3β reduces at‑level primary afferent growth responses associated with excitotoxic spinal cord injury dysesthesias
(2015-06-21)Background Neuropathic pain and sensory abnormalities are a debilitating secondary consequence of spinal cord injury (SCI). Maladaptive structural plasticity is gaining recognition for its role in contributing to the ... -
PI3K pan-inhibition impairs more efficiently proliferation and survival of T-cell acute lymphoblastic leukemia cell lines when compared to isoform-selective PI3K inhibitors
(2015-04)Class I phosphatidylinositol 3-kinases (PI3Ks) are frequently activated in T-cell acute lymphoblastic leukemia (T-ALL), mainly due to the loss of PTEN function. Therefore, targeting PI3Ks is a promising innovative approach ... -
A Pilot Study: The Effect of Healing Touch on Anxiety, Stress, Pain, Pain Medication Usage, and Physiological Measures in Hospitalized Sickle Cell Disease Adults Experiencing a Vaso-occlusive Pain Episode.
(East Carolina University, 2010)Sickle cell disease (SCD), a common genetic blood disorder affecting primarily African-Americans (Edwards, Scales, Loughlin, Bennett, Harris-Peterson, et al., 2005) causes a vaso-occlusive pain episode (VOPE) affecting ... -
Pitt County Memorial Hospital Plays a Role in the Eat Smart Move More North Carolina Movement
(2009)Pitt County Memorial Hospital is taking the "Journey to Excellence" and as part of that journey, is creating a culture of wellness. This paper describes those efforts as well as the criteria for healthy food. Data ... -
PKR Regulates B56 alpha-mediated BCL2 Phosphatase Activity in Acute Lymphoblastic Leukemia-derived REH Cells
(East Carolina University, 2009-12-19)Protein phosphatase 2A (PP2A) is a heterotrimer comprising catalytic, scaffold, and regulatory (B) subunits. There are at least 21 B subunit family members. Thus PP2A is actually a family of enzymes defined by which B ... -
PLC-beta 1 regulates the expression of miR-210 during mithramycin-mediated erythroid differentiation in K562 cells
(2014-06)PLC-beta 1 (PLCβ1) inhibits in human K562 cells erythroid differentiation induced by mithramycin (MTH) by targeting miR-210 expression. Inhibition of miR-210 affects the erythroid differentiation pathway and it occurs to ... -
Point of Care Ultrasound (PoCUS) by the Family Nurse Practitioner in the Primary Care Setting
(2017-04-19)Abstract Ultrasound (US) is currently found predominantly in specialty practices and is not generally utilized within the primary care environment at the point of care. While several medical schools have included US ... -
Poliomyelitis: History, Conquest and Cost Analysis
(2010-08-30)Laupus Library History Collections & the Department of Bioethics & Interdisciplinary Studies sponsor the History of Medicine Presentations as an educational service for the East Carolina University community. The Library ... -
Polypharmacy Among Older Adults in Long Term Care Facilities
(2020-04-29)Polypharmacy among older adults in long-term care facilities is a relevant issue, which leads to an increase in health care costs and adverse drug reactions. The implementation of comprehension medication reviews or ... -
Polypharmacy among Older Adults in Primary Care
(2018-11-19)Polypharmacy among community-dwelling older adults was identified as a significant problem facing primary care providers. Medication reconciliation was identified as a necessary process to aptly identify polypharmacy. ... -
Polytobacco use and multiple-product smoking among a random community sample of African-American adults
(2013)Objectives Little is known about polytobacco use among African-American adults. This study is the first to explore this among a random, statewide, community sample of African-American adults. Setting Community-based ... -
The Pong Principle
(2011-02-25)"Learning to Listen: A Patient Becomes the Teacher By Serving Up Life-Changing Advice -
Popular herb throughout the ages, dill packs flavor
(2022-03-09)This is a weekly Q and A newspaper column under the byline of Dr. Kathy Kolasa. The importance of today's column is to provide information to readers about dill weed, which is a popular herb that has been utilized for ages. ...