Browsing Health Sciences Campus by Title
Now showing items 527-546 of 564
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Transplantation of GABAergic Neurons but not Astrocytes Induces Recovery of Sensorimotor Function in the Traumatically Injured Brain
(East Carolina University, 2007-04-16)Embryonic stem (ES) cells have been investigated in many animal models of injury and disease. However, few studies have examined the ability of pre-differentiated ES cells to improve functional outcome following traumatic ... -
Treating problem solving deficits in traumatic brain injury
(East Carolina University, 2014)Cognitive deficits following TBI are multidimensional. Current treatment programs approach problem solving training in a top-down approach with problem solving skill perceived independent of attentional control and working ... -
Trends in esophageal cancer and body mass index by race and gender in the state of Michigan
(East Carolina University, 2009-06-23)Background: Adenocarcinoma of the esophagus has been increasing in incidence in the U.S. over the past several decades, particularly among white males. The factors driving the racial disparity in adenocarcinomas rates are ... -
Tropomyosin Dynamics in Cardiac Thin Filaments: A Multisite Förster Resonance Energy Transfer and Anisotropy Study
(East Carolina University, 2008-06)Cryoelectron microscopy studies have identified distinct locations of tropomyosin (Tm) within the Ca21-free, Ca21-saturated, and myosin-S1-saturated states of the thin filament. On the other hand, steady-state Förster ... -
Troponin-tropomyosin: an allosteric switch or a steric blocker?
(East Carolina University, 2002-08)The interaction of myosin subfragment 1 (S1) with actin-tropomyosin-troponin (regulated actin) is highly nucleotide dependent. The binding of S1 or S1-ADP (but not S1-ATP nor N,N - -phenylenedimaleimide-modified S1-ATP) ... -
Tumour necrosis factor-alpha regulates expression of the CCAAT-enhancer-binding proteins (C/EBPs) alpha and beta and determines the occupation of the C/EBP site in the promoter of the insulin-responsive glucose-transporter gene in 3T3-L1 adipocytes.
(East Carolina University, 1999-03-15)We have demonstrated previously that treatment of 3T3-L1 adipocytes with tumour necrosis factor-alpha (TNF) results in a rapid (4 h) and significant (75–80%) reduction in the rate of transcription of the GLUT4 gene. Control ... -
Two Distinct Pathways Supply Anthranilate as a Precursor of the Pseudomonas Quinolone Signal
(East Carolina University, 2007-05)Pseudomonas aeruginosa is an opportunistic pathogen that causes serious infections in immunocompromised patients and those with cystic fibrosis (CF). This gram-negative bacterium uses multiple cell-to-cell signals to control ... -
A two-component response regulator, gltR, is required for glucose transport activity in Pseudomonas aeruginosa PAO1.
(East Carolina University, 1996-10)A 729-bp open reading frame (gltR) was identified in Pseudomonas aeruginosa PAO1 that encodes a product homologous to the two-component response regulator family of proteins. Disruption of gltR caused loss of glucose ... -
The UHS Nutrition Initiative: Enhancing the ability of patients, employees and the community to "Eat Smart and Move More"
(2005)This article describes the obesity problem in eastern North Carolina and the responses that the Pitt County Memorial Hospital is taking locally to change policies and environments. -
Understanding the Role of Schools in Community Prevention of Childhood Obesity
(2014)Childhood obesity is considered an epidemic with the percentage of obesity among children in the United States more than tripling in the past 30 years (Institute of Medicine, 2012). Many factors in the environment contribute ... -
Unilateral Auditory Temporal Resolution Deficit: A Case Study
(East Carolina University, 1999)An adult with a unilateral precipitous severe high-frequency hearing loss displayed a selective auditory temporal resolution deficit in the poorer ear despite excellent word recognition ability in quiet bilaterally. Word ... -
Unique V3 Loop Sequence Derived from the R2 Strain of HIV-Type 1 Elicits Broad Neutralizing Antibodies
(East Carolina University, 2004-11)DNA vaccines expressing the envelope (Env) of the human immunodeficiency virus type 1 (HIV-1) have been relatively ineffective at generating high-titer, long-lasting, neutralizing antibodies. In this study, DNA vaccines ... -
Upregulation of Human T-Cell Leukemia Virus Type 1 Antisense Transcription by the Viral Tax Protein
(East Carolina University, 2009-02)Several studies have recently demonstrated the existence of human T-cell leukemia virus type 1 (HTLV-1) antisense transcripts, which allow the synthesis of the newly described HBZ protein. Although previous reports have ... -
The use of a personal fitness device in conjunction with online social networking as an effective delivery system for occupational therapy community practice to enhance an individual's personal occupation and self-efficacy
(East Carolina University, 2011)Participants wore a pedometer tracking device "fitbit" and participated in an on-line social support group daily. Data was collected through the "fitbit" including steps taken and distance traveled. Participants completed ... -
Use of a Pressure Vest to Reduce the Physiological Arousal of People with Profound Intellectual and Physical Disabilities During Routine Nail Care
(East Carolina University, 2009)This single subject ABAB study explored whether the use of a commercially available deep pressure vest would decrease physiological arousal in a male with profound mental retardation during nail care activities. ... -
The use of grounded theory to develop a framework for understanding student retention in community college nursing programs
(East Carolina University, 2013)Gaining admission into pre-licensure nursing programs has proven to be quite difficult for the average college student. Topping the list of crucial priorities for many academic institutions is the retention of these nursing ... -
Use of monoamine oxidase and redox enzymes in atrial tissue as novel predictors of postoperative atrial fibrillation
(East Carolina University, 2014)Postoperative atrial fibrillation (POAF) occurs in approximately 30% of cardiac surgery patients. The complication occurs despite advances in surgical procedures. It is associated with increased mortality, morbidity, and ... -
Use of Oral Language General Outcome Measures to Describe Children According to Language Status
(East Carolina University, 2011)The purpose of the study was to determine if short language samples can effectively distinguish children with language impairments from those who are typically developing. Four elicitation methods (individual picture ... -
Using a Household Food Inventory to Assess Food Variety and Availability Among Mothers in Residential Substance Abuse Recovery Programs
(East Carolina University, 2013)Obesity and substance abuse are two major public health issues in the United States, especially among low-income individuals. The United States Department of Health and Human Services has set forth the Dietary Guidelines, ... -
Using death to one's advantage: HIV modulation of apoptosis
(East Carolina University, 2001-03)Infection by human immunodeficiency virus (HIV) is associated with an early immune dysfunction and progressive destruction of CD4+ T lymphocytes. This progressive disappearance of T cells leads to a lack of immune control ...