Now showing items 565-584 of 1541

    • Genetic and hypoxic effects on germline tumor development in caenorhabditis elegans 

      Datla, Udaya Sree (East Carolina University, 2013)
      The process of differentiation of stem cells to committed, progenitor specific cell types is well studied but the reverse process of the dedifferentiation of these committed cells back to the undifferentiated state still ...
    • Genetic and Structural Analysis of the Bacteroides Conjugative Transposon CTn341 

      Bacic, Melissa K.; Parker, Anita C.; Stagg, J.; Whitley, H. P.; Wells, W. G.; Jacob, L. A.; Smith, C. J. (East Carolina University, 2005-04)
      The genetic structure and functional organization of a Bacteroides conjugative transposon (CTn), CTn341, were determined. CTn341 was originally isolated from a tetracycline-resistant clinical isolate of Bacteroides vulgatus. ...
    • Genetic control of cell fate specification in Caenorhabditis elegans germline. 

      Mamillapalli, Srivalli Swathi (East Carolina University, 2015)
      The precise regulation of germ cell fates (sperm or oocyte) lies at the heart of reproduction and fertility. The nematode Caenorhabditis elegans hermaphrodites produce a discrete number of sperm during larval development ...
    • Genetic Organization and Iron-Responsive Regulation of the Brucella abortus 2,3-Dihydroxybenzoic Acid Biosynthesis Operon, a Cluster of Genes Required for Wild-Type Virulence in Pregnant Cattle 

      Bellaire, Bryan H.; Elzer, Philip H.; Hagius, Sue; Walker, Joel; Baldwin, Cynthia L.; Roop, R. Martin II (East Carolina University, 2003-04)
      Brucella abortus reportedly produces the monocatechol siderophore 2,3-dihydroxybenzoic acid (2,3-DHBA) in response to iron limitation. Nucleotide sequence analysis of the cloned DHBA biosynthesis locus from virulent B. ...
    • Genome scan of human systemic lupus erythematosus: Evidence for linkage on chromosome 1q in African-American pedigrees 

      Moser, Kathy L.; Neas, Barbara R.; Salmon, Jane E.; Yu, Hua; Gray-McGuire, Courtney; Asundi, Neeraj; Bruner, Gail R.; Fox, Jerome; Kelly, Jennifer; Henshall, Stephanie; Bacino, Debra; Dietz, Myron; Hogue, Robert; Koelsch, Gerald; Nightingale, Lydia; Shaver, Tim; Abdou, Nabih I.; Albert, Daniel A.; Carson, Craig; Petri, Michelle; Treadwell, Edward L.; James, Judith A.; Harley, John B. (East Carolina University, 1998-12)
      Systemic lupus erythematosus (SLE) is an autoimmune disorder characterized by production of autoantibodies against intracellular antigens including DNA, ribosomal P, Ro (SS-A), La (SS-B), and the spliceosome. Etiology is ...
    • Genome-wide association study identifies multiple susceptibility loci for craniofacial microsomia 

      Zhang, Yong-Biao; Hu, Jintian; Zhang, Jiao; Zhou, Xu; Li, Xin; Gu, Chaohao; Liu, Tun; Xie, Yangchun; Liu, Jiqiang; Gu, Mingliang; Wang, Panpan; Wu, Tingting; Qian, Jin; Wang, Yue; Dong, Xiaoqun; Yu, Jun; Zhang, Qingguo (2016-02)
    • Genome-wide profiles of CtBP link metabolism with genome stability and epithelial reprogramming in breast cancer 

      Di, Li-Jun; Byun, Jung S.; Wong, Madeline M.; Wakano, Clay; Taylor, Tara; Bilke, Sven; Baek, Songjoon; Hunter, Kent; Yang, Howard; Lee, Maxwell; Zvosec, Celia; Khramtsova, Galina; Cheng, Fan; Perou, Charles M.; Miller, C. Ryan; Raab, Rachel; Olopade, Olufunmilayo I.; Gardner, Kevin (http://www.ncbi.nlm.nih.gov/pubmed/23385593, 2013-1)
    • The genomes of two key bumblebee species with primitive eusocial organization 

      Sadd, Ben M.; Barribeau, Seth M.; Bloch, Guy; de Graaf, Dirk C.; Dearden, Peter; Elsik, Christine G.; Gadau, Jürgen; Grimmelikhuijzen, Cornelis J.; Hasselmann, Martin; Lozier, Jeffrey D.; Robertson, Hugh M.; Smagghe, Guy; Stolle, Eckart; Van Vaerenbergh, Matthias; Waterhouse, Robert M.; Bornberg-Bauer, Erich; Klasberg, Steffen; Bennett, Anna K.; Câmara, Francisco; Guigó, Roderic; Hoff, Katharina; Mariotti, Marco; Munoz-Torres, Monica; Murphy, Terence; Santesmasses, Didac; Amdam, Gro V.; Beckers, Matthew; Beye, Martin; Biewer, Matthias; Bitondi, Márcia M.; Blaxter, Mark L.; Bourke, Andrew F.; Brown, Mark J.; Buechel, Severine D.; Cameron, Rossanah; Cappelle, Kaat; Carolan, James C.; Christiaens, Olivier; Ciborowski, Kate L.; Clarke, David F.; Colgan, Thomas J.; Collins, David H.; Cridge, Andrew G.; Dalmay, Tamas; Dreier, Stephanie; du Plessis, Louis; Duncan, Elizabeth; Erler, Silvio; Evans, Jay; Falcon, Tiago; Flores, Kevin; Freitas, Flávia C.; Fuchikawa, Taro; Gempe, Tanja; Hartfelder, Klaus; Hauser, Frank; Helbing, Sophie; Humann, Fernanda C.; Irvine, Frano; Jermiin, Lars S.; Johnson, Claire E.; Johnson, Reed M.; Jones, Andrew K; Kadowaki, Tatsuhiko; Kidner, Jonathan H.; Koch, Vasco; Köhler, Arian; Kraus, F. B.; Lattorff, H. M. G.; Leask, Megan; Lockett, Gabrielle A.; Mallon, Eamonn B.; Antonio, David S. Marco; Marxer, Monika; Meeus, Ivan; Moritz, Robin F.; Nair, Ajay; Näpflin, Kathrin; Nissen, Inga; Niu, Jinzhi; Nunes, Francis M.; Oakeshott, John G.; Osborne, Amy; Otte, Marianne; Pinheiro, Daniel G.; Rossié, Nina; Rueppell, Olav; Santos, Carolina G.; Schmid-Hempel, Regula; Schmitt, Björn D.; Schulte, Christina; Simões, Zilá L.; Soares, Michelle P.; Swevers, Luc; Winnebeck, Eva C.; Wolschin, Florian; Yu, Na; Zdobnov, Evgeny M.; Aqrawi, Peshtewani K.; Blankenburg, Kerstin P.; Coyle, Marcus; Francisco, Liezl; Hernandez, Alvaro G.; Holder, Michael; Hudson, Matthew E.; Jackson, LaRonda; Jayaseelan, Joy; Joshi, Vandita; Kovar, Christie; Lee, Sandra L.; Mata, Robert; Mathew, Tittu; Newsham, Irene F.; Ngo, Robin; Okwuonu, Geoffrey; Pham, Christopher; Pu, Ling-Ling; Saada, Nehad; Santibanez, Jireh; Simmons, DeNard; Thornton, Rebecca; Venkat, Aarti; Walden, Kimberly K.; Wu, Yuan-Qing; Debyser, Griet; Devreese, Bart; Asher, Claire; Blommaert, Julie; Chipman, Ariel D.; Chittka, Lars; Fouks, Bertrand; Liu, Jisheng; O’Neill, Meaghan P.; Sumner, Seirian; Puiu, Daniela; Qu, Jiaxin; Salzberg, Steven L.; Scherer, Steven E.; Muzny, Donna M.; Richards, Stephen; Robinson, Gene E.; Gibbs, Richard A.; Schmid-Hempel, Paul; Worley, Kim C. (2015-04-24)
      Background The shift from solitary to social behavior is one of the major evolutionary transitions. Primitively eusocial bumblebees are uniquely placed to illuminate the evolution of highly eusocial insect societies. ...
    • A germline-specific isoform of eIF4E (IFE-1) is required for efficient translation of stored mRNAs and maturation of both oocytes and sperm 

      Henderson, Melissa Anne; Cronland, Elizabeth; Dunkelbarger, Steve; Contreras, Vince; Strome, Susan; Keiper, Brett D. (East Carolina University, 2009-05-15)
      Fertility and embryonic viability are measures of efficient germ cell growth and development. During oogenesis and spermatogenesis, new proteins are required for both mitotic expansion and differentiation. Qualitative and ...
    • Gestational Diabetes Is Characterized by Reduced Mitochondrial Protein Expression and Altered Calcium Signaling Proteins in Skeletal Muscle 

      Boyle, Kristen E.; Hwang, Hyonson; Janssen, Rachel C.; DeVente, James E.; Barbour, Linda A.; Hernandez, Teri L.; Mandarino, Lawrence J.; Lappas, Martha; Friedman, Jacob E. (2014)
      The rising prevalence of gestational diabetes mellitus (GDM) affects up to 18% of pregnant women with immediate and long-term metabolic consequences for both mother and infant. Abnormal glucose uptake and lipid oxidation ...
    • Get exercise, information during Walk-With-A-Doc 

      Zeches, Breann A; Kolasa, Kathryn M (2020-09-30)
      This is a weekly Q and A newspaper column under the byline of Dr. Kathy Kolasa. Today's column highlights the importance of preventive health measures through 1-hour physical activity with local physicians.
    • Get the Lead Out! A Brief and Highly Selective History of Lead Poisoning. 

      Johnson, Bruce (2007-04-23)
      Laupus Library History Collections & the Department of Bioethics & Interdisciplinary Studies sponsor the History of Medicine Presentations as an educational service for the East Carolina University community. The Library ...
    • The Global Carbon Metabolism Regulator Crc Is a Component of a Signal Transduction Pathway Required for Biofilm Development by Pseudomonas aeruginosa 

      O'Toole, George A.; Gibbs, Karine A.; Hager, Paul W.; Phibbs, Paul V. Jr.; Kolter, Roberto (East Carolina University, 2000-01)
      The transition from a planktonic (free-swimming) existence to growth attached to a surface in a biofilm occurs in response to environmental factors, including the availability of nutrients. We show that the catabolite ...
    • Glycan Structures Contain Information for the Spatial Arrangement of Glycoproteins in the Plasma Membrane 

      Hall, M. Kristen; Weidner, Douglas A.; Chen, Jian ming; Bernetski, Christopher J.; Schwalbe, Ruth A. (2013)
    • Glycemic Control Patterns and Kidney Disease Progression among Primary Care Patients with Diabetes Mellitus 

      Cummings, Doyle M.; Larsen, Lars C.; Doherty, Lisa; Lea, C. Suzanne; Holbert, Donald (2011-07)
      Background: Reducing glycosylated hemoglobin (HbA1c) to near or less than 7% in patients with diabetes is associated with diminished microvascular complications, but this level is not consistently achieved. The purpose of ...
    • Granulocytic Sarcoma of the Male Breast in Acute Myeloblastic Leukemia with Concurrent Deletion of 5q and Trisomy 8 

      Rizwan, Muhammad; Islam, Md. Monirul; Rehman, Zia ur (2012)
      We describe a unique case of Granulocytic Sarcoma (GS) in a male, who presented to us with a painless right breast mass without any prior history of Leukemia. GS is an extramedullary tumor of myeloproliferative precursors ...
    • Gross Anatomy In the Library: Evaluating the Impact of Anatomical Models in Academic Health Sciences Libraries 

      Harmon, Geoffrey James Corey; Roby, Mary (2021-05)
      Background: Laupus Library began its anatomical model collection in the late 1980s with one model. In intervening years, the collection has grown to 236 models ranging from single organs to entire bodies. As of March 25, ...
    • Gross Anatomy:  Are Anatomical Models Worth the Investment? 

      Harmon, Geoffrey James Corey; Roby, Mary (2019-10-05)
      Our library began its anatomical model collection in the late 1980s with one model of the fetus. In intervening years, the collection has grown to 236 models ranging from single organs to entire bodies. As of July 1, 2019, ...
    • Group β Streptococcus Education for Pregnant Women at a Birth Center 

      Smith, Mandesa (2017-11-21)
      Group β Streptococcus (GBS) is an anaerobic Gram-positive bacteria that can colonize the genitourinary tract and place the newborn at risk for infection during the intrapartum and postnatal period. Due to this risk of ...
    • GSK-3 as potential target for therapeutic intervention in cancer 

      McCubrey, James A.; Steelman, Linda S.; Bertrand, Fred E.; Davis, Nicole Marie; Sokolosky, Melissa; Abrams, Stephen L.; Montalto, Giuseppe; D'Assoro, Antonino B.; Libra, Massimo; Nicoletti, Ferdinando; Maestro, Roberta; Basecke, Jorg; Rakus, Dariusz; Gizak, Agnieszka; Demidenko, Zoya N.; Cocco, Lucio; Martelli, Alberto M.; Cervello, Melchiorre (2014-05)
      The serine/threonine kinase glycogen synthase kinase-3 (GSK-3) was initially identified and studied in the regulation of glycogen synthesis. GSK-3 functions in a wide range of cellular processes. Aberrant activity of GSK-3 ...