Browsing Health Sciences Campus by Title

Now showing items 972-991 of 2624

  • Gene-environment interactions in sarcoidosis 

    Culver, Daniel A.; Newman, Lee S.; Kavuru, Mani S. (East Carolina University, 2007-05)
    Susceptibility to most human diseases is polygenic, with complex interactions between functional polymorphisms of single genes governing disease incidence, phenotype, or both. In this context, the contribution of any ...

  • Generation and characterization of the humoral immune response to DNA immunization with a chimeric beta-amyloid-interleukin-4 minigene 

    Ghochikyan, Anahit; Vasilevko, Vitaly; Petrushina, Irina; Movesesyan, Nina; Babikyan, Davit; Tian, Wenqiang; Sadzikava, Nadya; Ross, Ted M.; Head, Elizabeth; Cribbs, David H.; Agadjanyan, MIchael G. (East Carolina University, 2003-12)
    Active immunization with fibrillar beta-amyloid peptide (AB42) as well as passive transfer of anti-AB antibodies significantly reduces AB plaque deposition, neuritic dystrophy, and astrogliosis in the brain of mutant amyloid ...

  • Generational differences in practice site selection criteria amongst primary care physicians. 

    Duffrin, Christopher; Cashion, Molly; Cummings, Doyle M.; Whetstone, Lauren; Firnhaber, Jonathon; Levine, Gary; Watson, Ricky; Lambert, Aaron (2016)
    Background and Objectives: Generational differences are often viewed as shaping the overall attitudes and actions of different age cohorts. It is essential to understand the motivations and generational differences in ...

  • Generational differences in practice site selection criteria amongst primary care physicians. 

    Duffrin, Christopher; Cashion, Molly; Cummings, Doyle M.; Whetstone, Lauren; Firnhaber, Jonathon; Levine, Gary; Watson, Ricky; Lambert, Aaron (2016-01-25)
    Background and Objectives: Generational differences are often viewed as shaping the overall attitudes and actions of different age cohorts. It is essential to understand the motivations and generational differences in ...

  • Generators of mammalian vestibular surface responses to head motion 

    Gaines, Gary Christopher (East Carolina University, 2012)
    The linear vestibular sensory evoked potential (VsEP) is thought to be the compound electrical response of peripheral macular neurons and central neural relays, and as such used to directly assess macular function. The ...

  • Generic Medications and Blood Pressure Control in Diabetic Hypertensive Subjects 

    Cummings, Doyle M.; Letter, Abraham J.; Howard, George; Howard, Virginia J.; Safford, Monika M.; Prince, Valerie; Muntner, Paul (2013-03)
    OBJECTIVE To investigate temporal improvements in blood pressure (BP) control in subjects with diabetes and policy changes regarding generic antihypertensives. RESEARCH DESIGN AND METHODS In a cross-sectional study ...

  • Genetic and biochemical analysis of a novel Ambler class A β-Lactamase responsible for cefoxitin resistance in Bacteroides species. 

    Parker, Anita C.; Smith, C. Jeffrey (East Carolina University, 1993-05)
    A clinical isolate of Bacteroides vulgatus was resistant to tetracycline, clindamycin, ampicillin, cephaloridine, cefoxitin, and other 13-lactam antibiotics except imipenem. 13-Lactam resistance was mediated by a ...

  • Genetic and hypoxic effects on germline tumor development in caenorhabditis elegans 

    Datla, Udaya Sree (East Carolina University, 2013)
    The process of differentiation of stem cells to committed, progenitor specific cell types is well studied but the reverse process of the dedifferentiation of these committed cells back to the undifferentiated state still ...

  • Genetic and Structural Analysis of the Bacteroides Conjugative Transposon CTn341 

    Bacic, Melissa K.; Parker, Anita C.; Stagg, J.; Whitley, H. P.; Wells, W. G.; Jacob, L. A.; Smith, C. J. (East Carolina University, 2005-04)
    The genetic structure and functional organization of a Bacteroides conjugative transposon (CTn), CTn341, were determined. CTn341 was originally isolated from a tetracycline-resistant clinical isolate of Bacteroides vulgatus. ...

  • Genetic control of cell fate specification in Caenorhabditis elegans germline. 

    Mamillapalli, Srivalli Swathi (East Carolina University, 2015)
    The precise regulation of germ cell fates (sperm or oocyte) lies at the heart of reproduction and fertility. The nematode Caenorhabditis elegans hermaphrodites produce a discrete number of sperm during larval development ...

  • Genetic Organization and Iron-Responsive Regulation of the Brucella abortus 2,3-Dihydroxybenzoic Acid Biosynthesis Operon, a Cluster of Genes Required for Wild-Type Virulence in Pregnant Cattle 

    Bellaire, Bryan H.; Elzer, Philip H.; Hagius, Sue; Walker, Joel; Baldwin, Cynthia L.; Roop, R. Martin II (East Carolina University, 2003-04)
    Brucella abortus reportedly produces the monocatechol siderophore 2,3-dihydroxybenzoic acid (2,3-DHBA) in response to iron limitation. Nucleotide sequence analysis of the cloned DHBA biosynthesis locus from virulent B. ...

  • Genetic Testing to Inform Epilepsy Treatment Management From an International Study of Clinical Practice 

    Boutlier, Susan B.; et al (2022-10-31)

  • Genetically Increasing Flux Through b-Oxidation in Skeletal Muscle Increases Mitochondrial Reductive Stress and Glucose Intolerance 

    Smith, Cody D.; Lin, Chien-Te; McMillin, Shawna L.; Weyrauch, Luke A.; Schmidt, Cameron A.; Smith, Cheryl A.; Witczak, Carol; Neufer, P. Darrell; Kurland, Irwin J. (2021)

  • Genome scan of human systemic lupus erythematosus: Evidence for linkage on chromosome 1q in African-American pedigrees 

    Moser, Kathy L.; Neas, Barbara R.; Salmon, Jane E.; Yu, Hua; Gray-McGuire, Courtney; Asundi, Neeraj; Bruner, Gail R.; Fox, Jerome; Kelly, Jennifer; Henshall, Stephanie; Bacino, Debra; Dietz, Myron; Hogue, Robert; Koelsch, Gerald; Nightingale, Lydia; Shaver, Tim; Abdou, Nabih I.; Albert, Daniel A.; Carson, Craig; Petri, Michelle; Treadwell, Edward L.; James, Judith A.; Harley, John B. (East Carolina University, 1998-12)
    Systemic lupus erythematosus (SLE) is an autoimmune disorder characterized by production of autoantibodies against intracellular antigens including DNA, ribosomal P, Ro (SS-A), La (SS-B), and the spliceosome. Etiology is ...

  • Genome Sequences for Two Acinetobacter baumannii Strains Obtained Using the Unicycler Hybrid Assembly Pipeline 

    Farrow, John M. ,III; Pesci, Everett C.; Slade, Daniel (2021-03-11)

  • Genome-wide association study identifies multiple susceptibility loci for craniofacial microsomia 

    Zhang, Yong-Biao; Hu, Jintian; Zhang, Jiao; Zhou, Xu; Li, Xin; Gu, Chaohao; Liu, Tun; Xie, Yangchun; Liu, Jiqiang; Gu, Mingliang; Wang, Panpan; Wu, Tingting; Qian, Jin; Wang, Yue; Dong, Xiaoqun; Yu, Jun; Zhang, Qingguo (2016-02)

  • Genome-wide profiles of CtBP link metabolism with genome stability and epithelial reprogramming in breast cancer 

    Di, Li-Jun; Byun, Jung S.; Wong, Madeline M.; Wakano, Clay; Taylor, Tara; Bilke, Sven; Baek, Songjoon; Hunter, Kent; Yang, Howard; Lee, Maxwell; Zvosec, Celia; Khramtsova, Galina; Cheng, Fan; Perou, Charles M.; Miller, C. Ryan; Raab, Rachel; Olopade, Olufunmilayo I.; Gardner, Kevin (http://www.ncbi.nlm.nih.gov/pubmed/23385593, 2013-1)

  • The genomes of two key bumblebee species with primitive eusocial organization 

    Sadd, Ben M.; Barribeau, Seth M.; Bloch, Guy; de Graaf, Dirk C.; Dearden, Peter; Elsik, Christine G.; Gadau, Jürgen; Grimmelikhuijzen, Cornelis J.; Hasselmann, Martin; Lozier, Jeffrey D.; Robertson, Hugh M.; Smagghe, Guy; Stolle, Eckart; Van Vaerenbergh, Matthias; Waterhouse, Robert M.; Bornberg-Bauer, Erich; Klasberg, Steffen; Bennett, Anna K.; Câmara, Francisco; Guigó, Roderic; Hoff, Katharina; Mariotti, Marco; Munoz-Torres, Monica; Murphy, Terence; Santesmasses, Didac; Amdam, Gro V.; Beckers, Matthew; Beye, Martin; Biewer, Matthias; Bitondi, Márcia M.; Blaxter, Mark L.; Bourke, Andrew F.; Brown, Mark J. F.; Buechel, Severine D.; Cameron, Rossanah; Cappelle, Kaat; Carolan, James C.; Christiaens, Olivier; Ciborowski, Kate L.; Clarke, David F.; Colgan, Thomas J.; Collins, David H.; Cridge, Andrew G.; Dalmay, Tamas; Dreier, Stephanie; du Plessis, Louis; Duncan, Elizabeth; Erler, Silvio; Evans, Jay D.; Falcon, Tiago; Flores, Kevin; Freitas, Flávia C.; Fuchikawa, Taro; Gempe, Tanja; Hartfelder, Klaus; Hauser, Frank; Helbing, Sophie; Humann, Fernanda C.; Irvine, Frano; Jermiin, Lars S.; Johnson, Claire E.; Johnson, Reed M.; Jones, Andrew K; Kadowaki, Tatsuhiko; Kidner, Jonathan H.; Koch, Vasco; Köhler, Arian; Kraus, F. B.; Lattorff, H. M. G.; Leask, Megan; Lockett, Gabrielle A.; Mallon, Eamonn B.; Antonio, David S. Marco; Marxer, Monika; Meeus, Ivan; Moritz, Robin F.; Nair, Ajay; Näpflin, Kathrin; Nissen, Inga; Niu, Jinzhi; Nunes, Francis M.; Oakeshott, John G.; Osborne, Amy; Otte, Marianne; Pinheiro, Daniel G.; Rossié, Nina; Rueppell, Olav; Santos, Carolina G.; Schmid-Hempel, Regula; Schmitt, Björn D.; Schulte, Christina; Simões, Zilá L.; Soares, Michelle P.; Swevers, Luc; Winnebeck, Eva C.; Wolschin, Florian; Yu, Na; Zdobnov, Evgeny M.; Aqrawi, Peshtewani K.; Blankenburg, Kerstin P.; Coyle, Marcus; Francisco, Liezl; Hernandez, Alvaro G.; Holder, Michael; Hudson, Matthew E.; Jackson, LaRonda; Jayaseelan, Joy; Joshi, Vandita; Kovar, Christie; Lee, Sandra L.; Mata, Robert; Mathew, Tittu; Newsham, Irene F.; Ngo, Robin; Okwuonu, Geoffrey; Pham, Christopher; Pu, Ling-Ling; Saada, Nehad; Santibanez, Jireh; Simmons, DeNard; Thornton, Rebecca; Venkat, Aarti; Walden, Kimberly K.; Wu, Yuan-Qing; Debyser, Griet; Devreese, Bart; Asher, Claire; Blommaert, Julie; Chipman, Ariel D.; Chittka, Lars; Fouks, Bertrand; Liu, Jisheng; O’Neill, Meaghan P.; Sumner, Seirian; Puiu, Daniela; Qu, Jiaxin; Salzberg, Steven L.; Scherer, Steven E.; Muzny, Donna M.; Richards, Stephen; Robinson, Gene E.; Gibbs, Richard A.; Schmid-Hempel, Paul; Worley, Kim C. (2015-04-24)
    Background The shift from solitary to social behavior is one of the major evolutionary transitions. Primitively eusocial bumblebees are uniquely placed to illuminate the evolution of highly eusocial insect societies. ...

  • A Genotype–Phenotype Analysis of Glutathione Peroxidase 4 in Human Atrial Myocardium and Its Association with Postoperative Atrial Fibrillation 

    Akhter, Shahab A.; Berdaweel, Islam A.; Hart, Alexander A.; Jatis, Andrew J.; Karlan, Nathan; Gaine, Marie E.; Smith, Ryan M.; Anderson, Ethan (2022-04-06)

  • The Germ Cell-Specific RNA Binding Protein RBM46 is Essential for Spermatogonial Differentiation in Mice 

    Johnson, Taylor A.; Geyer, Christopher B. (2022-09-21)