Browsing Division of Health Sciences by Title
Now showing items 4-23 of 1364
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A COMPARISON OF THE EFFICACY OF KEYBOARDING WITHOUT TEARS PROGRAM AND MIXED METHOD INSTRUCTION
(East Carolina University, 2018-11-27)The purpose of this study was to investigate the two-year impact of using the Keyboarding Without Tears[trademark] instruction program compared to a mixed method instruction approach on students' net typing words per minute ... -
A Grounded Theory Study to Understand Nurse and Resident Physician Communication Dynamics
(East Carolina University, 2017-05-03)Communication between nurses and physicians frequently occurs in the delivery of care to patients in the acute healthcare setting. In an environment where a person's life and well-being depends upon accurate communication, ... -
A phenomenological investigation of Spanish-English bilingual supervisees’ experience in clinical supervision
(East Carolina University, 2016-07-20)With a growing number of American households speaking languages other than English, the counseling profession must meet the counseling needs of non-English speaking clients. In turn, clinical supervisors and counselor ... -
A QUEST FOR ARTICULAR CARTILAGE PROGENITOR CELLS LEADS TO TEMPORAL REGULATION OF HYALURONAN REQUIRED FOR 3T3-L1 ADIPOGENESIS
(East Carolina University, 2017-07-13)During embryogenesis, mesenchymal progenitor cells exhibit hyaluronan-dependent pericellular matrices as a major component of the extracellular matrix. As connective tissues form by cellular condensations, there is a loss ... -
Abdominal Abscess to Zygote: The Spectrum of Foci for a Health Science Librarian Liaison
(East Carolina University, 2005-05-16)Keeping clients informed of changes and new databases. -
Abraham Flexner and the black medical schools.
(East Carolina University, 2006-09)"Abraham Flexner and the Black Medical Schools" first appeared in Beyond Flexner: Medical Education in the Twentieth Century, Barbara Barzansky and Norman Gevitz, eds. Copyright 1992 by Barbara Barzansky and Norman Gevitz. ... -
Absence of unsaturated fatty acid synthesis in murine T lymphocytes.
(East Carolina University, 1989-08)Stearic acid is toxic for T lymphocytes in vitro but has little effect on B lymphocytes. To investigate the molecular basis for this difference, purified murine T and B lymphocytes were compared for their abilities to ... -
The Academic Health Sciences Library and Serial Selection
(East Carolina University, 1974-07)A review of efforts to formulate basic medical journal lists and a report of a survey of subscriptions held in academic health science libraries is presented. The subscriptions held by thirty-seven libraries were analyzed ... -
Acceptability of Activity Monitor Use During and After Hospitalization in Older Adults with Heart Failure
(East Carolina University, 2018-05-03)Background: Many activity monitors have been validated and accepted to track physical activity in adults, however research is limited in clinical populations such as older adults with heart failure. Health tends to decline ... -
Acidic tumor microenvironment and pH-sensing G protein-coupled receptors
(2013-10)The tumor microenvironment is acidic due to glycolytic cancer cell metabolism, hypoxia, and deficient blood perfusion. It is proposed that acidosis in the tumor microenvironment is an important stress factor and selection ... -
Acidosis Activation of the Proton-Sensing GPR4 Receptor Stimulates Vascular Endothelial Cell Inflammatory Responses Revealed by Transcriptome Analysis
(2013)Acidic tissue microenvironment commonly exists in inflammatory diseases, tumors, ischemic organs, sickle cell disease, and many other pathological conditions due to hypoxia, glycolytic cell metabolism and deficient blood ... -
Acidosis Decreases c-Myc Oncogene Expression in Human Lymphoma Cells: A Role for the Proton-Sensing G Protein-Coupled Receptor TDAG8
(2013-10)Acidosis is a biochemical hallmark of the tumor microenvironment. Here, we report that acute acidosis decreases c-Myc oncogene expression in U937 human lymphoma cells. The level of c-Myc transcripts, but not mRNA or protein ... -
The Actin Binding Protein, Fesselin, is a Member of the Synaptopodin Family
(East Carolina University, 2008-07)Fesselin is a natively unfolded protein that is abundant in avian smooth muscle. Like many natively unfolded proteins, fesselin has multiple binding partners including actin, myosin, calmodulin and α-actinin. Fesselin ... -
Activation of GPR4 by Acidosis Increases Endothelial Cell Adhesion through the cAMP/Epac Pathway
(2011)Endothelium-leukocyte interaction is critical for inflammatory responses. Whereas the tissue microenvironments are often acidic at inflammatory sites, the mechanisms by which cells respond to acidosis are not well understood. ... -
Activation of the proton sensing G-protein coupled receptor, GPR4, regulates focal adhesion dynamics and delays cell spreading due to increased cytoskeletal tension
(East Carolina University, 2013)The tumor microenvironment is characteristically acidic due to insufficient blood perfusion, chronic inflammation, hypoxia, and altered cell metabolism. The low pH found in the tumor microenvironment may facilitate the ... -
Activity of the novel mTOR inhibitor Torin-2 in B-precursor acute lymphoblastic leukemia and its therapeutic potential to prevent Akt reactivation
(2014-10)The PI3K/Akt/mTOR signaling cascade is a key regulatory pathway controlling cell growth and survival, and its dysregulation is a reported feature of B-precursor acute lymphoblastic leukemia (B-pre ALL). Torin-2 is a ... -
Acute Adverse Effects of Fine Particulate Air Pollution on Ventricular Repolarization
(2010-07)Background The mechanisms for the relationship between particulate pollution and cardiac disease are not fully understood. Objective We examined the effects and time course of exposure to fine particulate matter ≤ 2.5 ... -
Acute Effects of Fine Particulate Air Pollution on Cardiac Arrhythmia: The APACR Study
(2011-03)Background: The mechanisms underlying the relationship between particulate matter (PM) air pollution and cardiac disease are not fully understood. Objectives: We examined the effects and time course of exposure to fine ... -
Adaptations of Pseudomonas aeruginosa to the Cystic Fibrosis Lung Environment Can Include Deregulation of zwf, Encoding Glucose-6-Phosphate Dehydrogenase
(East Carolina University, 2005-11)Cystic fibrosis (CF) patients are highly susceptible to chronic pulmonary disease caused by mucoid Pseudomonas aeruginosa strains that overproduce the exopolysaccharide alginate. We showed here that a mutation in zwf, ...