Now showing items 264-283 of 336

  • Radioprotective Effect of American Ginseng on Human Lymphocytes at 90 Minutes Post-irradiation: A Study of 40 Cases 

    Lee, Tung-Kwang; O'Brien, Kevin F.; Wang, Weidong; Johnke, Roberta M.; Sheng, Chao; Benhabib, Sidi Mohammed; Wang, Tao; Allison, Ron R. (East Carolina University, 2010-05)
    Backgroundâ Ionizing radiation (IR) initiates intracellular oxidative stress through enhanced formation of reactive oxygen species (ROS) that attack DNA leading to cell death. As the diversity of IR applied in medicine, ...
  • Raf-Induced Vascular Endothelial Growth Factor Augments Kaposi's Sarcoma-Associated Herpesvirus Infection 

    Hamden, Khalief E.; Ford, Patrick W.; Whitman, Audy G.; Dyson, Ossie F.; Cheng, Shi-Yuan; McCubrey, James A.; Akula, Shaw M. (East Carolina University, 2004-12)
    Recombinant green fluorescent protein encoding Kaposi’s sarcoma-associated herpesvirus (rKSHV.152) infection of -estradiol stimulated human foreskin fibroblasts (HFF) or HFF/ B-Raf[FF]:ER (expressing a weaker form of ...
  • Raman spectroscopy: the gateway into tomorrow's virology 

    Lambert, Phelps J.; Whitman, Audy G.; Dyson, Ossie F.; Akula, Shaw M. (East Carolina University, 2006-06-28)
    In the molecular world, researchers act as detectives working hard to unravel the mysteries surrounding cells. One of the researchers' greatest tools in this endeavor has been Raman spectroscopy. Raman spectroscopy is a ...
  • Rat-bite fever as a cause of septic arthritis: a diagnostic dilemma. 

    Rumley, Richard L.; Patrone, Nicholas A.; White, Lindsey (East Carolina University, 1987-10)
    Rat-bite fever results from an infection with the organism Streptobacillus moniliformis. Symptomatic patients often present with fever, malaise, cough, maculopapular rash, and occasional arthritis, and usually have a history ...
  • RecA and RadA Proteins of Brucella abortus Do Not Perform Overlapping Protective DNA Repair Functions following Oxidative Burst 

    Roux, Christelle M.; Booth, Natha J.; Bellaire, Bryan H.; Gee, Jason M.; Roop, R. Martin II; Kovach, Michael E.; Tsolis, Renee M.; Elzer, Philip H.; Ennis, Don G. (East Carolina University, 2006-07)
    Very little is known about the role of DNA repair networks in Brucella abortus and its role in pathogenesis. We investigated the roles of RecA protein, DNA repair, and SOS regulation in B. abortus. While recA mutants in ...
  • The Redox-Sensitive Transcriptional Activator OxyR Regulates the Peroxide Response Regulon in the Obligate Anaerobe Bacteroides fragilis 

    Rocha, Edson R.; Owens, Gary Jr; Smith, C. Jeffrey (East Carolina University, 2000-09)
    The peroxide response-inducible genes ahpCF, dps, and katB in the obligate anaerobe Bacteroides fragilis are controlled by the redox-sensitive transcriptional activator OxyR. This is the first functional oxidative ...
  • Regulation of KSHV replication by glycoprotein B: chronicles of a virus and its host 

    Dyson, Ossie F. (East Carolina University, 2011)
    Kaposi's sarcoma-associated herpesvirus (KSHV), the causative agent of three cancers: Kaposi's sarcoma (KS), primary effusion lymphoma (PEL), and the plasmablastic form of multicentric Castleman disease (MCD), shares many ...
  • The regulation of anthranilate synthesis for the production of pqs in pseudomonas aeruginosa 

    Knoten, Claire A. (East Carolina University, 2013)
    The ubiquitous bacterium P. aeruginosa is an important human pathogen that causes devastating infections in immunocompromised patients and chronic infections in cystic fibrosis patients. The ability of P. aeruginosa to ...
  • Regulation of Bacteriodes fragilis katB mRNA by oxidative stress and carbon limitation. 

    Rocha, Edson R.; Smith, C. Jeffrey (East Carolina University, 1997-11)
    Regulation of the katB catalase gene in the anaerobic bacterium Bacteroides fragilis was studied. Northern blot hybridization analyses revealed that katB was transcribed as an approximately 1.6-kb monocistronic mRNA. The ...
  • Regulation of lipoprotein lipase mRNA content in 3T3-L1 cells by tumour necrosis factor. 

    Cornelius, Peter; Enerback, Sven; Bjursell, Gunnar; Olivecrona, Thomas; Pekala, Phillip H. (East Carolina University, 1988-02-01)
    Tumour necrosis factor (TNF) was previously shown to suppress lipoprotein lipase (LPL) synthesis and activity in 3T3-L1 adipocytes. The present study examined the effect ofTNF on amounts ofmRNA for LPL in 3T3-Ll cells. ...
  • Regulation of Pseudomonas Quinolone Signal Synthesis in Pseudomonas aeruginosa 

    Wade, Dana S.; Calfee, M. Worth; Rocha, Edson R.; Ling, Elizabeth A.; Engstrom, Elana; Coleman, James P.; Pesci, Everett C. (East Carolina University, 2005-07)
    Pseudomonas aeruginosa is an opportunistic pathogen that causes chronic lung infections in cystic fibrosis patients and is a major source of nosocomial infections. This bacterium controls many virulence factors by using ...
  • Reporting and Concordance of Methodologic Criteria Between Abstracts and Articles in Diagnostic Test Studies 

    Estrada, Carlos A.; Bloch, Richard M.; Antonacci, Diana; Basnight, Lorraine; Patel, Sangnya T.; Patel, Sanjay C.; Wiese, Wilhelmine (East Carolina University, 2000-03)
    OBJECTIVE: To evaluate the quality and concordance of methodologic criteria in abstracts versus articles regarding the diagnosis of trichomoniasis. STUDY DESIGN: Survey of published literature. DATA SOURCES: ...
  • Resolving the Role of POU1F1 in Human Growth Hormone Locus Activation 

    Hunsaker, Tamra Leigh (East Carolina University, 2012)
    The human growth hormone gene ( hGH-N) is regulated by a distal locus control region (LCR) composed of five deoxyribonuclease I hypersensitive sites (HSs). The region encompassing HSI and HSII contains the predominant ...
  • Response to Kuhse 

    Perkin, R. M.; Resnik, D. B. (East Carolina University, 2002-08)
    In this short paper, we respond to critics of our original paper, The agony of agonal respiration: is the last gasp necessary?. A common thread in both Hawryluckâ s and Kuhseâ s responses is the difficulties encountered ...
  • Results From the Periodontitis and Vascular Events (PAVE) Study: A Pilot Multicentered, Randomized, Controlled Trial to Study Effects of Periodontal Therapy in a Secondary Prevention Model of Cardiovascular Disease 

    Offenbacher, Steven; Beck, James D.; Moss, Kevin; Mendoza, Luisito; Paquette, David W.; Barrow, David A.; Couper, David J.; Steward, Dawn D.; Falkner, Karen L.; Graham, Susan P.; Grossi, Sara; Gunsolley, John C.; Madden, Theresa; Maupome, Gerardo; Trevisan, Maurizio; Van Dyke, Thomas E.; Genco, Robert J. (East Carolina University, 2009-02)
    Background- In the Periodontitis and Vascular Events (PAVE) pilot study, periodontal therapy was provided as an intervention in a secondary cardiac event prevention model through five coordinated cardiac-dental centers. ...
  • Review of Musculoskeletal Injuries and Prevention in the Endoscopy Practitioner 

    Harvin, Glenn (2014-08)
    Practitioners of endoscopy often experience musculoskeletal pain and injury (most often in the back, neck, shoulders, hands, wrists, and thumbs) that are associated with the minute and repetitive strain that is placed on ...
  • Review: Carbon Nanotubes and Chronic Granulomatous Disease 

    Barna, Barbara P.; Judson, Marc A.; Thomassen, Mary Jane (2014-06-23)
    Use of nanomaterials in manufactured consumer products is a rapidly expanding industry and potential toxicities are just beginning to be explored. Combustion-generated multiwall carbon nanotubes (MWCNT) or nanoparticles ...
  • The Ripped Cava 

    Cunningham, Paul R. G.; Foil, M. Beth (East Carolina University, 1995-04)
    Lacerations of the inferior vena cava are associated with a high mortality and may be difficult to repair. The majority of injuries are due to penetrating trauma. Rapid transportation to definitive surgical care with ...
  • Robotic Surgical Training in an Academic Institution 

    Chitwood, W. Randolph; Nifong, L. Wiley; Chapman, William H. H.; Felger, Jason E.; Bailey, B. Marcus; Ballint, Tara; Mendleson, Kim G.; Kim, Victor B.; Young, James A.; Albrecht, Robert A. (East Carolina University, 2001-10)
    Objective To detail robotic procedure development and clinical applications for mitral valve, biliary, and gastric reflux operations, and to implement a multispecialty robotic surgery training curriculum for both ...
  • The Role of Axl and Axl-like Proteins in Murine Spermatogenesis 

    Thompson, Kristjan Louise (East Carolina University, 2009)
    Mice lacking the Axl receptor tyrosine kinase (RTK) and its family members exhibit detrimental effects on their reproductive ability. AXL is localized to Sertoli cells, which are the major nurturing cells in the seminiferous ...