Browsing Brody School of Medicine by Subject "Neoplasms"
Now showing items 1-3 of 3
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Comparison of Mitochondrial Phenotypes Across Cancers with Different Tissues of Origin
(East Carolina University, 2021-12-06)Cancer metabolism is typically characterized by aerobic glycolysis, an increase in glucose uptake and lactate production despite adequate sufficient oxygen availability to support mitochondrial oxidative phosphorylation ... -
p53 and NGAL: dual regulatory roles in advanced prostate cancer
(East Carolina University, 2011)The development of prostate cancer from small regions of hyperplasia to invasive tumors requires genetic and epigenetic alterations of critical cellular components to aid in the development of cells more adapted for aberrant ... -
PPP1R42 is a positive regulator of PP1 in centrosome duplication and separation and cilia dynamics
(East Carolina University, 2014)The centrosome is a dynamic structure that undergoes structural and functional transitions, which are coordinated with the cell cycle. It functions as the microtubule organizing center (MTOC) in interphase, duplicates and ...