Now showing items 1-4 of 4
Increased DJ-1 expression under oxidative stress and in Alzheimer's disease brains
(East Carolina University, 2009-02-25)
Mutations in the DJ-1 gene have been linked to autosomal recessive familial Parkinson's disease. To understand the function of DJ-1, we determined the DJ-1 expression in both zebrafish and post mortem human brains. We found ...
delta-Catenin promotes prostate cancer cell growth and progression by altering cell cycle and survival gene profiles
(East Carolina University, 2009-03-10)
Background: delta-Catenin is a unique member of delta-catenin/armadillo domain superfamily proteins and its primary expression is restricted to the brain. However, delta-catenin is upregulated in human prostatic adenocarcinomas, ...
Identification of Extracellular d-Catenin Accumulation for Prostate Cancer Detection
(East Carolina University, 2009-03-01)
BACKGROUND—Prostate cancer is the second leading cause of cancer death in men, and early detection is essential to reduce mortality and increase survival. δ-Catenin is a unique β-catenin superfamily protein primarily ...
Increased nucleotide polymorphic changes in the 5'-untranslated region of δ-catenin (CTNND2) gene in prostate cancer
(East Carolina University, 2009-01)
Cancer pathogenesis involves multiple genetic and epigenetic alterations, which result in oncogenic changes in gene expression. δ-Catenin (CTNND2) is overexpressed in cancer although the mechanisms of its upregulation are ...