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Inhibition by rapamycin of ornithine decarboxylase and epithelial cell proliferation in intestinal IEC-6 cells in culture
(East Carolina University, 1997-02)
1 Induction of the enzyme ornithine decarboxylase (ODC) appears to be controlled primarily at the
level of ODC mRNA translation. The immunosuppressant drug, rapamycin, blocked the induction of
ODC in response to serum ...
Alveolar macrophage priming by intravenous administration of chitin particles, polymers of N-acetyl-D-glucosamine, in mice
(East Carolina University, 1997-03)
Intravenous (i.v.) administration of phagocytosable chitin particles (1 to 10 mm) in C57BL/6 mice and SCID mice primed alveolar macrophages (Mf) within 3 days to yield up to a 50-fold increase in their oxidative burst when ...
The Bacteroides mobilizable transposon Tn4555 integrates by a site-specific recombination mechanism similar to that of the gram-positive bacterial element Tn916
(East Carolina University, 1997-04)
The Bacteroides mobilizable transposon Tn4555 is a 12.2-kb molecule that encodes resistance to cefoxitin. Conjugal transposition is hypothesized to occur via a circular intermediate and is stimulated by coresident tetracycline ...
Ectopic expression of Hel-N1, an RNA-binding protein, increases glucose transporter (GLUT1) expression in 3T3-L1 adipocytes.
(East Carolina University, 1997-02)
3T3-L1 preadipocytes ectopically expressing the mammalian RNA-binding protein Hel-N1 expressed up to 10-fold more glucose transporter (GLUT1) protein and exhibited elevated rates of basal glucose uptake. Hel-N1 is a member ...
Regulation of Bacteriodes fragilis katB mRNA by oxidative stress and carbon limitation.
(East Carolina University, 1997-11)
Regulation of the katB catalase gene in the anaerobic bacterium Bacteroides fragilis was studied. Northern
blot hybridization analyses revealed that katB was transcribed as an approximately 1.6-kb monocistronic
mRNA. The ...
The pseudorabies virus UL28 protein enters the nucleus after coexpression with the herpes simplex virus UL15 protein
(East Carolina University, 1997-12)
Herpesvirus DNA is packaged into capsids in the nuclei of infected cells in a process requiring at least six
viral proteins. Of the proteins required for encapsidation of viral DNA, UL15 and UL28 are the most conserved
among ...
Method of treating adenosine depletion
(1997-08-26)
A method of treating adenosine depletion in a subject in need of such treatment is disclosed. The method comprises administering to the subject folinic acid or a pharmaceutically acceptable salt thereof in an amount effective ...
A composition comprising nerve growth factor and 2-amino-1,1,3-tricyano-1-propene useful for the induction, stimulation, and maintenance of nerve growth, and methods of potentiating choline O-acetyltransferase and tyrosine hydroxylase by 2-amino-1,1,3-tricyano-1-propene are disclosed.
(1997-09-09)
A composition comprising nerve growth factor and 2-amino-1,1,3-tricyano-1-propene useful for the induction, stimulation, and maintenance of nerve growth, and methods of potentiating choline O-acetyltransferase and tyrosine ...
Comparison of identifications of human and animal source gram-negative bacteria by API 20E and crystal E/NF systems.
(East Carolina University, 1997-01)
This study compared the abilities of API 20E and BBL Crystal E/NF identification systems to correctly identify human and animal source gram-negative bacilli of known identifications, as provided by the American Type Culture ...
Hypothesis for induction and propagation of chemical sensitivity based on biopsy studies.
(East Carolina University, 1997-03)
The reactive airways dysfunction syndrome (RADS), the reactive upper airways dysfunction
syndrome (RUDS), the sick building syndrome (SBS), and the multiple chemical sensitivity
syndrome (MCS) are overlapping disorders ...