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Rapid development of Purkinje cell excitability, functional cerebellar circuit, and afferent sensory input to cerebellum in zebrafish
(2014-12-19)
The zebrafish has significant advantages for studying the morphological development of the brain. However, little is known about the functional development of the zebrafish brain. We used patch clamp electrophysiology in ...
Preventable hospital admissions among the homeless in California: A retrospective analysis of care for ambulatory care sensitive conditions
(2014-10)
Background: Limited research exists that investigates hospital admissions for ambulatory care sensitive conditions
(ACSCs) among the homeless, who frequently lack a usual source of care. This study profiled ACSC admissions ...
Roles of neutrophil gelatinase-associated lipocalin (NGAL) in human cancer
(2014-02-01)
Cancer remains one of the major cause of death in the Western world. Although, it has been demonstrated that new therapies can improve the outcome of cancer patients, still many patients relapse after treatment. Therefore, ...
Root parasitic plant Orobanche aegyptiaca and shoot parasitic plant Cuscuta australis obtained Brassicaceae-specific strictosidine synthase-like genes by horizontal gene transfer
(2014)
Background
Besides gene duplication and de novo gene generation, horizontal gene transfer (HGT) is another important way of acquiring new genes. HGT may endow the recipients with novel phenotypic traits that are important ...
Risk-adapted targeted intraoperative radiotherapy versus whole-breast radiotherapy for breast cancer:5-year results for local control and overall survival from the TARGIT-A randomised trial
(2014-02-14)
The TARGIT-A trial compared risk-adapted radiotherapy using single-dose targeted intraoperative radiotherapy (TARGIT) versus fractionated external beam radiotherapy (EBRT) for breast cancer. We report 5-year results for ...
Smooth wavelet approximations of truncated Legendre polynomials via the Jacobi theta function
(2014-10-16)
The family of nth order q-Legendre polynomials are introduced. They are shown to be obtainable from the Jacobi theta function and to satisfy recursion relations and multiplicatively advanced differential equations (MADEs) ...
The extracellular domain of myelin oligodendrocyte glycoprotein elicits atypical experimental autoimmune encephalomyelitis in rat and Macaque species
(2014-10-14)
Atypical models of experimental autoimmune encephalomyelitis (EAE) are advantageous in that the heterogeneity of clinical signs appears more reflective of those in multiple sclerosis (MS). Conversely, models of classical ...
The evolution of photosynthesis in chromist algae through serial endosymbioses
(2014-12-10)
Chromist algae include diverse photosynthetic organisms of great ecological and social importance. Despite vigorous research efforts, a clear understanding of how various chromists acquired photosynthetic organelles has ...
The "Goldilocks Zone" from a redox perspective-Adaptive vs. deleterious responses to oxidative stress in striated muscle
(2014-09-18)
Consequences of oxidative stress may be beneficial or detrimental in physiological systems. An organ system's position on the “hormetic curve” is governed by the source and temporality of reactive oxygen species (ROS) ...
The cyclic-di-GMP signaling pathway in the Lyme disease spirochete, Borrelia burgdorferi
(2014-05-01)
In nature, the Lyme disease spirochete Borrelia burgdorferi cycles between the unrelated environments of the Ixodes tick vector and mammalian host. In order to survive transmission between hosts, B. burgdorferi must be ...