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A Bayesian machine scientist to aid in the solution of challenging scientific problems
(2020-01-31)
Closed-form, interpretable mathematical models have been instrumental for advancing our understanding of the world; with the data revolution, we may now be in a position to uncover new such models for many systems from ...
Influence of density and salinity on larval development of salt-adapted and salt-naïve frog populations
(2020-01-08)
Environmental change and habitat fragmentation will affect population densities for many species. For those species that have locally adapted to persist in changed or stressful habitats, it is uncertain how density ...
Developing Concept Enriched Models for Big Data Processing Within the Medical Domain
(2020-07)
Within the past few years, the medical domain has endeavored to incorporate artificial intelligence, including cognitive computing tools, to develop enriched models for processing and synthesizing knowledge from Big Data. ...
Dose-Dependent Effects of GLD-2 and GLD-1 on Germline Differentiation and Dedifferentiation in the Absence of PUF-8
(2020-01-24)
PUMILIO/FBF (PUF) proteins have a conserved function in stem cell regulation.
Caenorhabditis elegans PUF-8 protein inhibits the translation of target mRNAs by
interacting with PUF binding element (PBE) in the 30 untranslated ...
Characterization of METTL16 as a cytoplasmic RNA binding protein
(2020-01-15)
mRNA modification by N6-methyladenosine (m6A) is involved in many post-transcriptional
regulation processes including mRNA stability, splicing and promotion of translation.
Accordingly, the recently identified mRNA ...
The lhfpl5 Ohnologs lhfpl5a and lhfpl5b Are Required for Mechanotransduction in Distinct Populations of Sensory Hair Cells in Zebrafish
(2020-01-15)
Hair cells sense and transmit auditory, vestibular, and hydrodynamic information by
converting mechanical stimuli into electrical signals. This process of mechano-electrical
transduction (MET) requires a mechanically ...
Stratifying Intraductal Papillary Mucinous Neoplasms by Cyst Fluid Analysis: Present and Future
(2020-02-09)
A significant proportion of patients with intraductal papillary mucinous neoplasms (IPMNs)
undergo surgical resection in order to prevent or treat pancreatic cancer at the risk of significant
perioperative morbidity. ...