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Cytotoxic and Pathogenic Properties of Klebsiella oxytoca Isolated from Laboratory Animals
(2014-07)
Klebsiella oxytoca is an opportunistic pathogen implicated in various clinical diseases in animals and humans. Studies suggest that in humans K. oxytoca exerts its pathogenicity in part through a cytotoxin. However, cytotoxin ...
Therapeutic targeting of CK2 in acute and chronic leukemias
(2018-01)
Phosphorylation can regulate almost every property of a protein and is involved in all fundamental cellular processes. Thus, proper regulation of phosphorylation events is critical to the homeostatic functions of cell ...
Response and resilience of Spartina alterniflora to sudden dieback
(2016-08)
We measured an array of biophysical and spectral variables to evaluate the response and recovery of Spartina alterniflora to a sudden dieback event in spring and summer 2004 within a low marsh in coastal Virginia, USA. S. ...
Efficacy and tolerability of pegloticase for the treatment of chronic gout in patients refractory to conventional treatment: Two randomized controlled trials
(2011-08-17)
Context Patients with chronic disabling gout refractory to conventional urate-lowering therapy need timely treatment to control disease manifestations related to tissue urate crystal deposition. Pegloticase, monomethoxyp ...
Sarcoidosis activates diverse transcriptional programs in bronchoalveolar lavage cells
(2016-07)
Background: Sarcoidosis is a multisystem immuno-inflammatory disorder of unknown etiology that most
commonly involves the lungs. We hypothesized that an unbiased approach to identify pathways activated in
bronchoalveolar ...
TNM cancer staging: can it help develop a novel staging system for type 2 diabetes?
(2018-11-28)
Abstract: Type 2 diabetes (DM2) constitutes 90%–95% of the diabetes cases and is increasing at an alarming rate in the world. The Centers for Disease Control and Prevention (CDC) esti- mates that more than 29 million people ...
Variation in female aggression in 2 three-spined stickleback populations with female throat and spine coloration
(2018-03-07)
Despite growing interest in female ornament evolution, we still have a rudimentary understanding of female display traits relative to similar traits in males. Under one popular adaptive scenario, fe- male ornaments are ...
Relationship between overall child development and caries severity in Chilean three-year-old preschool children.
(2016-11-11)
To determine the relationship between caries and overall child development in three-year-old children in the cities of Linares and Talca, Chile, 2014-2015. Method: Cross-sectional study conducted in a sample of 170 preschool ...