Now showing items 21-25 of 25

  • Phorbol esters induce death in MCF-7 breast cancer cells with altered expression of protein kinase C isoforms. Role for p53-independent induction of gadd-45 in initiating death. 

    de Vente, James E.; Kukoly, Cynthia A.; Bryant, Winifred O.; Posekany, Karla J.; Chen, Jianming; Fletcher, Donald J.; Parker, Peter J.; Pettit, George J.; Lozano, Guillermina; Cook, Paul P.; Ways, D. Kirk (East Carolina University, 1995-10)
    Protein kinase C (PKC) modulates growth, differentiation, and apoptosis in a cell-specific fashion. Overexpression of PKC-a in MCF-7 breast cancer cells (MCF-7-PKC-a cell) leads to expression of a more transformed phenotype. ...
  • Statins induce lethal effects in acute myeloblastic lymphoma cells within 72 hours 

    Burke, Lillian P.; Kukoly, Cynthia A. (East Carolina University, 2008-02)
    HMG-CoA Reductase inhibitors (statins) induce apoptosis in acute myeloid leukemia (AML) cells in vitro; however, the concentrations associated with cell death in AML cells are higher than those clinically tolerated during ...
  • Postvaccinial (influenza) disseminated encephalopathy (Brown-Sequard syndrome). 

    Antony, Suresh J.; Fleming, D. Frank; Bradley, Teresa K. (East Carolina University, 1995-09)
    This article reports a case of Brown-Sequard syndrome that occurred in a patient following the administration of trivalent influenza vaccine. The patient responded well to intravenous steroids and physical therapy. This ...
  • Quantum dot labeling of mesenchymal stem cells 

    Muller-Borer, Barbara J.; Collins, Maria C.; Gunst, Philip R.; Cascio, Wayne E.; Kypson, Alan P. (East Carolina University, 2007-11-07)
    Background: Mesenchymal stem cells (MSCs) are multipotent cells with the potential to differentiate into bone, cartilage, fat and muscle cells and are being investigated for their utility in cell-based transplantation ...
  • Mechanisms controlling the acquisition of a cardiac phenotype by liver stem cells 

    Muller-Borer, Barbara J.; Cascio, Wayne E.; Esch, Gwyn L.; Kim, Hyung-Suk; Coleman, William B.; Grisham, Joe W.; Anderson, Page A. W.; Malouf, Nadia N. (East Carolina University, 2007-03-06)
    The mechanisms underlying stem cell acquisition of a cardiac phenotype are unresolved. We studied early events during the acquisition of a cardiac phenotype by a cloned adult liver stem cell line (WB F344) in a cardiac ...