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The role of PPARÎ³ in carbon nanotube-elicited granulomatous lung inflammation
BACKGROUND: Although granulomatous inflammation is a central feature of many disease processes, cellular mechanisms of granuloma formation and persistence are poorly understood. Carbon nanoparticles, which can be products ...
Sarcoidosis activates diverse transcriptional programs in bronchoalveolar lavage cells
Abstract Background Sarcoidosis is a multisystem immuno-inflammatory disorder of unknown etiology that most commonly involves the lungs. We hypothesized that an unbiased ...