Now showing items 1-1 of 1

    • Small Molecule, Non-Peptide p75NTR Ligands Inhibit Aß-Induced Neurodegeneration and Synaptic Impairment 

      Yang, Tao; Knowles, Juliet K.; Lu, Qun; Zhang, Hong; Arancio, Ottavio; Moore, Laura A.; Chang, Timothy; Wang, Qian; Andreasson, Katrin; Rajadas, Jayakumar; Fuller, Gerald G.; Xie, Youmei; Massa, Stephen M.; Longo, Frank M. (East Carolina University, 2008-11-03)
      The p75 neurotrophin receptor (p75NTR) is expressed by neurons particularly vulnerable in Alzheimer’s disease (AD). We tested the hypothesis that non-peptide, small molecule p75NTR ligands found to promote survival signaling ...