Browsing Pharmacology and Toxicology by Author "Nyce, Jonathan W."
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Composition, formulations & method for prevention & treatment of diseases and conditions associated with bronchoconstriction, allergy(ies) & inflammation
Nyce, Jonathan W. (2004-11-30)A pharmaceutical composition effective for preventing and alleviating bronchoconstriction, lung allergy(ies) and inflammation comprises a surfactant and an oligonucleotide anti-sense to an adenosine receptor gene, flanking ... -
Low adenosine agent, composition, kit and method for treatment of airway disease
Nyce, Jonathan W.; Metzger, James (1999-11-30)An oligonucleotide which is antisense to a mRNA encoding a polypeptide involved in airway disease(s) contains up to three adenosines per every 21 nucleotide a method of treating airway disease in a subject in need of such ... -
Method of treating adenosine depletion
Nyce, Jonathan W. (1997-08-26)A method of treating adenosine depletion in a subject in need of such treatment is disclosed. The method comprises administering to the subject folinic acid or a pharmaceutically acceptable salt thereof in an amount effective ... -
Neuropeptide Y analogues, compositions and methods of lowering blood pressure
Nyce, Jonathan W.; Leonard, Sherry Ann (2000-06-13)Neuropeptide Y analogues, and their compositions are effective for lower blood pressure. -
Specific antisense oligonucleotide composition & method for treatment of disorders associated with bronchoconstriction and lung inflammation
Nyce, Jonathan W. (2000-03-21)A DNA comprises an oligonucleotide antisense to mRNA encoding an adenosine A.sub.1 or A.sub.3 receptor. The oligo is provided as a composition, various formulations, a capsule, and cartridge and in the form of a kit. The ...