Browsing Pharmacology and Toxicology by Author "Oh, Minsoo"
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Delta-Catenin Induced Dendritic Morphogenesis: An Essential Role of p190RhoGEF Interaction through Akt1 Mediated Phosphorylation
Kim, Hangun; Han, Jeong-Ran; Park, Jaejun; Oh, Minsoo; James, Sarah E.; Chang, Sunghoe; Lu, Qun; Lee, Kwang Youl; Ki, Hyunkyoung; Song, Woo-Joo; Kwonseop, Kim (East Carolina University, 2008-01-11)delta-Catenin was first identified through its interaction with Presenilin-1 and has been implicated in the regulation of dendrogenesis and cognitive function. However, the molecular mechanisms by which delta-catenin ... -
E-Cadherin negatively modulates delta-catenin-induced morphological changes and RhoA activity reduction by competing with p190RhoGEF for delta-catenin
Kim, Hangun; Oh, Minsoo; Lu, Qun; Kim, Kwonseop (East Carolina University, 2008-12-12)δ-Catenin is a member of the p120-catenin subfamily of armadillo proteins. Here, we describe distinctive features of δ-catenin localization and its association with E-cadherin in HEK293 epithelial cells. In HEK293 cells ... -
Identification of E2F1 as a positive transcriptional regulator for delta-catenin
Kim, Kwonseop; Oh, Minsoo; Ki, Hyunkyoung; Wang, Tao; Bareiss, Sonja; Fini, M. Elizabeth; Li, Dawei; Lu, Qun (East Carolina University, 2008-05-02)Delta-Catenin is upregulated in human carcinomas. However, little is known about the potential transcriptional factors that regulate delta-catenin expression in cancer. Using a human delta-catenin reporter system, we have ...