Abu Deiab, Ghina’a I.Al-Huniti, Mohammed H.Hyatt, I. F. DempseyNagy, Emma E.Gettys, Kristen E.Sayed, Sommayah S.Joliat, Christine M.Daniel, Paige E.Vummalaneni, Rupa M.Morehead, Andrew T. Jr.Sargent, Andrew L.Croatt, Mitchell P.2020-04-172020-04-172017-02-28http://hdl.handle.net/10342/8171Dienoic acids and pentadienyl alcohols are coupled in a decarboxylative and dehydrative manner at ambient temperature using Pd(0) catalysis to generate 1,3,6,8-tetraenes. Contrary to related decarboxylative coupling reactions, an anion-stabilizing group is not required adjacent to the carboxyl group. Of mechanistic importance, it appears that both the diene of the acid and the diene of the alcohol are required for this reaction. To further understand this reaction, substitutions at every unique position of both cou- pling partners was examined and two potential mechanisms are presented.Article10.3762/bjoc.13.41