Langley, Ricky L.Treadwell, Edward L.2011-04-152011-05-172011-04-152011-05-171994-02Journal of the National Medical Association; 86:2 p. 149-153http://hdl.handle.net/10342/3336Pericardial disorders occurring in connective tissue diseases are not uncommon and may present as acute or chronic pericarditis with or without an effusion. In many instances, a diagnosis of pericardial involvement is not found until autopsy. Echocardiography and other currently employed radiographic techniques have enhanced the ability to make a diagnosis. Approximate frequencies of common connective tissue disorders with pericardial involvement include scleroderma (59%), systemic lupus erythematosus (44%), mixed connective tissue disease (30%), rheumatoid arthritis (24%), and polymyositis/dermatomyositis (11%). Cardiac tamponade or constriction is rare. This article describes a patient with clinical features consistent with mixed connective tissue disease that presented with a pericardial effusion and cardiac tamponade. In addition, a review of pericardial involvement in connective tissue diseases and the occurrence of cardiac tamponade or constriction is included. Originally published Journal of the National Medical Association, Vol. 86, No. 2, Feb 1994en-USAuthor notified of opt-out rights by Cammie Jennings prior to upload of this article.Pericardial disordersMixed connective tissue diseaseCardiac tamponadeArticlePMC2568178