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ACTING "WHITE": THE UNSPOKEN, UNDERSTOOD HIERARCHY OF BLACKNESS
(East Carolina University, 2020-01-09)This thesis will examine how a variety of extenuating factors serve to complicate a black person's self-identity, as well as determine acceptance or exclusion from the black community in the United States. The introductory ... -
Activation of GPR4 by Acidosis Increases Endothelial Cell Adhesion through the cAMP/Epac Pathway
(2011)Endothelium-leukocyte interaction is critical for inflammatory responses. Whereas the tissue microenvironments are often acidic at inflammatory sites, the mechanisms by which cells respond to acidosis are not well understood. ... -
Activation of GPR4 by acidosis inhibits tumor cell migration, invasion and metastasis.
(East Carolina University, 2011)Melanoma and Prostate Cancer are two of the most diagnosed forms of cancer in the United States. The ability to metastasize and colonize in a distant location is one of the most devastating hallmarks of cancer as modes ... -
Activation of the proton sensing G-protein coupled receptor, GPR4, regulates focal adhesion dynamics and delays cell spreading due to increased cytoskeletal tension
(East Carolina University, 2013)The tumor microenvironment is characteristically acidic due to insufficient blood perfusion, chronic inflammation, hypoxia, and altered cell metabolism. The low pH found in the tumor microenvironment may facilitate the ... -
Active Measures: Then and Now
(2020-06-25)A term used to refer to Soviet efforts to influence and manipulate public opinion in other countries during the Cold War, Active Measures has gained a newfound currency in light of the 2016 election influence campaign by ... -
The Activist's Daughter
(East Carolina University, 1997)Appearing in the North Carolina Books column, this article reviews Ellyn Bache's The Activist's Daughter. -
Activity of the novel mTOR inhibitor Torin-2 in B-precursor acute lymphoblastic leukemia and its therapeutic potential to prevent Akt reactivation
(2014-10)The PI3K/Akt/mTOR signaling cascade is a key regulatory pathway controlling cell growth and survival, and its dysregulation is a reported feature of B-precursor acute lymphoblastic leukemia (B-pre ALL). Torin-2 is a ... -
Actual neighborhood-level crime predicts body mass index z-score changes in a multi-racial/ethnic sample of children
(2018-09-24)Longitudinal studies are warranted to clarify the influence crime has on health outcomes in children especially children representing multiple racial/ethnic backgrounds. To address this need, the current study examined whether ... -
Acute Adverse Effects of Fine Particulate Air Pollution on Ventricular Repolarization
(2010-07)Background The mechanisms for the relationship between particulate pollution and cardiac disease are not fully understood. Objective We examined the effects and time course of exposure to fine particulate matter ≤ 2.5 ... -
ACUTE CARE NURSES’ KNOWLEDGE ON IN-HOSPITAL STROKES AND PREDICTORS OF KNOWLEDGE
(East Carolina University, 2023-04-21)In-hospital strokes (IHS) account for one in five strokes; however, IHS patients have higher mortality and are half as likely to be discharged home when compared to community-occurring strokes (Chen et al., 2018). Nurse-driven ... -
THE ACUTE EFFECTS OF COMMON PHYSICAL THERAPY INTERVENTIONS ON PASSIVE HAMSTRING STIFFNESS: A BLINDED RANDOMIZED CONTROLLED TRIAL
(2019-04-01)Purpose/Hypothesis : The purpose of this study was to compare the effects of common physical therapy techniques on acute hamstring muscle passive stiffness. The hypothesis is that dry needling, stretching, and foam rolling ...