Browsing by Title
Now showing items 1836-1855 of 2003
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Thermodynamic and Spectroscopic Investigations of Novel Antimicrobial Peptides containing Unnatural Amino Acids with Model Membrane Systems
(East Carolina University, 2011)With the over prescription and use of antibiotic drugs the evolution of drug resistant bacteria strains has become a world wide health crisis. In response to this crisis, the search for new drugs to kill bacteria via a ... -
Thermodynamic Investigation into the Binding Properties of Cardiac Troponin (Human and Bovine)
(East Carolina University, 2010)Troponin is an integral protein in the mechanism of muscle contraction. In order to induce cardiac muscle contraction, Ca[superscript]2[superscript]+ must bind to the TnC subunit (calcium binding subunit) of troponin to ... -
Thermodynamic Investigation of Copper Binding to the Amyloid-Beta (A[beta]) Peptide
(East Carolina University, 2010)Alzheimer's disease is a fatal and neurodegenerative disease with as many as 5.3 million Americans living with the disease. One of the characteristic hallmarks of Alzheimer's is the amyloid plaques that build up around the ... -
Thermodynamic Investigations into Copper Binding in the N-Terminal Region of the Prion Protein at Low Copper Loadings
(East Carolina University, 2010)The prion protein (PrP) is a naturally occurring protein found at high levels in central nervous system (CNS). The misfolding of the PrP is responsible for neurodegenerative diseases called transmissible spongioform ... -
"They Would Have a Law of Their Own" : The Discourse on Smuggling at the Old Bailey, 1736-1814
(East Carolina University, 2013)This thesis examines the cases of 136 men tried for smuggling offenses at London's central criminal court during the long eighteenth century. Before the 1770s, the government portrayed smuggling as a crime against the ... -
Thinking Outside of the (Classroom) Box: Collaboration to Enhance Pedagogy
(2012-03-29)RCAW Scholar-Teacher Award -
Thioredoxin Reductase Is Essential for Thiol/Disulfide Redox Control and Oxidative Stress Survival of the Anaerobe Bacteroides fragilis
(East Carolina University, 2007-11)Results of this study showed that the anaerobic, opportunistic pathogen Bacteroides fragilis lacks the glutathione/glutaredoxin redox system and possesses an extensive number of putative thioredoxin (Trx) orthologs. ... -
Thoracic neuroblastoma presenting as a cystic hygroma.
(East Carolina University, 1988-10)A case of thoracic neuroblastoma with extension into the supraclavicular fossa is described. By physical examination and ultrasound the patient was thought to have a cystic hygroma with mediastinal extension. A 'cystic' ... -
Thoracolumbar compression fractures presenting with an acute ileus.
(East Carolina University, 1990-09)Corticosteroids are commonly used in the treatment of connective tissue diseases such as systemic lupus erythematosus. Although they are usually efficacious, osteoporosis leading to spine compression fractures is not ... -
Three Generations, One Future: A Systematic Analysis on Nicotine's Effect across generations in C. elegans.
(East Carolina University, 2013)Tobacco smoking is a worldwide epidemic that is responsible for diseases and death rates that surpass those attributed to a combination of other causes (e.g. cancer, HIV, accidents). A major mediator of tobacco-smoke related ... -
Thrown Voices : A Series of Dramatic Monologues, With a Discussion of the Genre
(East Carolina University, 2010)This thesis examines the complex nature of the poetic genre of the dramatic monologue by providing multiple perspectives on the genre--namely, those of the literary critic and the creative writer. This thesis provides a ... -
Time Series Forecasting: How Much prologue is the Past
(2013-04-11) -
Tinigible Body Macrophages in Regulation of Germinal Center Reactions
(East Carolina University, 1998)Tingible body macrophages (TBM), long thought simply as scavengers of apoptotic lymphocytes, are located in the unique microenvironment of germinal centers in close proximity to antigen-retaining follicular dendritic cells ... -
TMEFF2 is an epigenetic modulator that promotes androgen independent growth in castration-resistant prostate cancer cells
(East Carolina University, 2014)While the ability to detect PCa has improved significantly due to PSA screenings, the survival rate for men diagnosed with PCa has remained stagnant, and the disease remains the second leading cause of cancer related deaths ... -
Tools for Risk and Emergency Communication (Panel)
(2013-05-22)After the welcoming remarks, Dr. Kain introduced the first panel theme of communication and introduced the speakers. Her presentation, Social Media Management Systems (not included in the video), overviews the tools ... -
Tourism and the Dare County Economy
(2009-05) -
Tourism, Pilgrimage, and Development in Bodhgaya, Bihar, India
(East Carolina University, 2012)In 2002, the Mahabodhi Temple, located in Bodhgaya, Bihar, India, became a UNESCO World Heritage Site, a designation that reflects both the site's religious and cultural significance. While Bodhgaya is considered the ... -
Toward increasing leadership capacity in nurses: an exploration of the state and future perspectives of leadership education in pre-licensure baccalaureate nursing programs.
(East Carolina University, 2015)The purpose of this study was to explore and describe the state and future perspectives of leadership education in pre-licensure baccalaureate nursing programs. Study objectives were to describe nurse educator and practice ... -
Toward Relational Craft
(East Carolina University, 2011)This thesis report contends with the contemporary context of studio craft here in the USA. Studio craft is predicated on habits of a modern world, and the political and economic relations comprising our social landscape ... -
Towards a Method for the Analysis of Experimental Music
(East Carolina University, 2014)This paper discusses the nature of experimental music, its reception, and suggests a method for its analysis. It gives a definition for this body of music and traces its historical development. A continuum is constructed ...