Browsing by Title
Now showing items 1876-1895 of 2003
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Trends in esophageal cancer and body mass index by race and gender in the state of Michigan
(East Carolina University, 2009-06-23)Background: Adenocarcinoma of the esophagus has been increasing in incidence in the U.S. over the past several decades, particularly among white males. The factors driving the racial disparity in adenocarcinomas rates are ... -
Tropomyosin Dynamics in Cardiac Thin Filaments: A Multisite Förster Resonance Energy Transfer and Anisotropy Study
(East Carolina University, 2008-06)Cryoelectron microscopy studies have identified distinct locations of tropomyosin (Tm) within the Ca21-free, Ca21-saturated, and myosin-S1-saturated states of the thin filament. On the other hand, steady-state Förster ... -
Troponin-tropomyosin: an allosteric switch or a steric blocker?
(East Carolina University, 2002-08)The interaction of myosin subfragment 1 (S1) with actin-tropomyosin-troponin (regulated actin) is highly nucleotide dependent. The binding of S1 or S1-ADP (but not S1-ATP nor N,N - -phenylenedimaleimide-modified S1-ATP) ... -
THE TRUE ROLE OF RECESS ACCORDING TO REGULAR AND SPECIAL EDUCATORS
(East Carolina University, 2013)Due to recent trends to eliminate or reduce the time devoted towards school recess, the current study investigates the experiences and overall perceptions of school recess held by both regular and special veteran educators. ... -
Trusting Digital Preservation for Print Collection Management, Or How Librarians Should Learn to Stop Worrying and Love the "E"
(2011-09)This article advocates planning for the management of print collections in light of digital preservation activities. Three activities include deduplicating print holdings from archival online journal packages, participating ... -
The Tub and Other Stories
(East Carolina University, 2012)This portfolio of creative writing includes four full-length short stories and two pieces of flash fiction. In each of the full-length stories, a male protagonist gets caught up in circumstances over which he has little ... -
Tumor Growth Induces Oxidative Clustered DNA Lesions Damage in Distant Mouse Tissue in vivo
(East Carolina University, 2010)Our goal was to ascertain if DNA damage induced by oxidative stress is capable of being exploited as a precancerous or cancer biomarker. The specific DNA damage that we assessed was oxidatively induced non-DSB clustered ... -
Tumour necrosis factor-alpha regulates expression of the CCAAT-enhancer-binding proteins (C/EBPs) alpha and beta and determines the occupation of the C/EBP site in the promoter of the insulin-responsive glucose-transporter gene in 3T3-L1 adipocytes.
(East Carolina University, 1999-03-15)We have demonstrated previously that treatment of 3T3-L1 adipocytes with tumour necrosis factor-alpha (TNF) results in a rapid (4 h) and significant (75–80%) reduction in the rate of transcription of the GLUT4 gene. Control ... -
TWITTER AND SPORTS COMMUNICATION: THE EFFECT ON ATHLETES, ORGANIZATIONS AND THE TRADITIONAL MEDIA
(2015)Since its advent, Twitter has had a significant impact on sports communication. This essay examines the effect that Twitter has had on athletes, sports leagues and the media itself. It includes a review of recent and ... -
Two Distinct Pathways Supply Anthranilate as a Precursor of the Pseudomonas Quinolone Signal
(East Carolina University, 2007-05)Pseudomonas aeruginosa is an opportunistic pathogen that causes serious infections in immunocompromised patients and those with cystic fibrosis (CF). This gram-negative bacterium uses multiple cell-to-cell signals to control ... -
A two-component response regulator, gltR, is required for glucose transport activity in Pseudomonas aeruginosa PAO1.
(East Carolina University, 1996-10)A 729-bp open reading frame (gltR) was identified in Pseudomonas aeruginosa PAO1 that encodes a product homologous to the two-component response regulator family of proteins. Disruption of gltR caused loss of glucose ... -
Types of Forecast and Weather-Related Information Used among Tourism Businesses in Coastal North Carolina
(East Carolina University, 2014)This study profiles the coastal tourism sector, a large and diverse consumer of climate and weather information. It is crucial to provide reliable, accurate and relevant resources for the climate and weather-sensitive ... -
The UHS Nutrition Initiative: Enhancing the ability of patients, employees and the community to "Eat Smart and Move More"
(2005)This article describes the obesity problem in eastern North Carolina and the responses that the Pitt County Memorial Hospital is taking locally to change policies and environments. -
UInterestManager : A Generic Framework to Model User Interests
(East Carolina University, 2013)With the proliferation of documents on the Internet, it has become increasingly difficult for users to search and retrieve the information they want: information that is relevant and interesting. To address this problem, ... -
Ukraine's Destination Image as Perceived by U.S. College Students
(East Carolina University, 2010)The present study is an exploration of Ukraine's destination image as viewed by U.S. college students. Student market is a rapidly growing one and presents opportunities for emerging destinations like Ukraine. A combination ... -
Understanding Counterproductive Work Behavior : Aggressive Employees' Responses to Leader-Member Exchange
(East Carolina University, 2013)This study provides further understanding of the integrative model of counterproductive work behavior (CWB). Specifically, it examined the antecedents of counterproductive work behavior as a function of both traits (i.e., ... -
Understanding Cultural Self-Efficacy Among Medical Students
(2015)Cultural competency has become an integral factor in healthcare over the past couple decades. The most frequently assessed component of cultural competency is the concept of cultural self-efficacy. Cultural self-efficacy ... -
Understanding the Role of Schools in Community Prevention of Childhood Obesity
(2014)Childhood obesity is considered an epidemic with the percentage of obesity among children in the United States more than tripling in the past 30 years (Institute of Medicine, 2012). Many factors in the environment contribute ... -
Unilateral Auditory Temporal Resolution Deficit: A Case Study
(East Carolina University, 1999)An adult with a unilateral precipitous severe high-frequency hearing loss displayed a selective auditory temporal resolution deficit in the poorer ear despite excellent word recognition ability in quiet bilaterally. Word ... -
Unique V3 Loop Sequence Derived from the R2 Strain of HIV-Type 1 Elicits Broad Neutralizing Antibodies
(East Carolina University, 2004-11)DNA vaccines expressing the envelope (Env) of the human immunodeficiency virus type 1 (HIV-1) have been relatively ineffective at generating high-titer, long-lasting, neutralizing antibodies. In this study, DNA vaccines ...