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Now showing items 2074-2093 of 6589
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EphrinA1-Fc attenuates myocardial ischemia/ reperfusion injury in mice
(2017-12-13)EphrinA1, a membrane-bound receptor tyrosine kinase ligand expressed in healthy car- diomyocytes, is lost in injured cells following myocardial infarction. Previously, we have reported that a single intramyocardial injection ... -
Epigenetic Effect of Modified Diet and Exercise on Drosophila Metabolic Phenotype and Cardiovascular Health
(2015-04)Obesity is a growing world-wide epidemic. Overweight populations are prone to a variety of morbid conditions including diabetes type 2, cardiovascular diseases, and cancers. The catastrophic increase in obesity rates, which ... -
Epigenetic mechanisms of drug resistance: drug-induced DNA hypermethylation and drug resistance.
(East Carolina University, 1993-04-01)In a model system employing Chinese hamster V-79 cells, the DNA synthesis inhibitor 3'-azido-3'- deoxythymidine (BW A509U, AZT) was shown to induce genome-wide DNA hypermethylation, low-frequency silencing of thymidine ... -
Epigenetic re-wiring of breast cancer by pharmacological targeting of C-terminal binding protein
(2019-08-08)The C-terminal binding protein (CtBP) is an NADH-dependent dimeric family of nuclear proteins that scaffold interactions between transcriptional regulators and chromatin-modifying complexes. Its association with poor ... -
Epigenome-Wide Analyses Identify Two Novel Associations With Recurrent Stroke in the Vitamin Intervention for Stroke Prevention Clinical Trial Citation metadata
(2018-09-06)DNA methylation, a well-characterized epigenetic modification that is influenced by both environment and genetic variation, has previously been implicated in a number of complex diseases, including cardiovascular disease ... -
Equilibration and Exchange of Fluorescently Labeled Molecules in Skeletal Muscle Fibers Studied Using Confocal Microscopy
(East Carolina University, 1995-04)Diffusion of molecules into skinned muscle fibers is often necessary when studying muscle contraction and its regulation. Usually, it is assumed that diffusion of molecules is fast also in the structured system of a muscle ... -
Equitable rationing of highly specialised health care services for children: a perspective from South Africa.
(East Carolina University, 1999-06)The principles of equality and equity, respectively in the Bill of Rights and the white paper on health, provide the moral and legalfoundations forfuture health care for children in South Africa. However, given extreme ... -
EQUITY AGENTS: CREATING AN INNOVATIVE LEARNING CULTURE WITH FOREIGN TEACHERS AND LĂOSHĪ 老师 WITHIN AN INTERNATIONAL SCHOOL
(East Carolina University, 2019-04-23)Educators within international school contexts are proponents of equity and believe that they listen to and advocate for the local teaching assistants, aides, and staff. However, issues of power, organizational structures, ... -
EQUITY AND ACCESS : EXAMINING OPPORTUNITIES OF ADVANCED PLACEMENT FOR AFRICAN AMERICAN STUDENTS
(East Carolina University, 2014)This research study used Invitational Education Theory to examine the attitudes and perceptions educators have concerning college-level coursework and the potential impact these attitudes and perceptions had on the ... -
An Ergonomic Evaluation of a Front Support Chair for Forward Leaning Seated Tasks
(East Carolina University, 2014)The prevalence of low back pain in industry has contributed to employee days away from work and therefore decreased production. Low back pain is even more pervasive in industries where the work requires the employee to ... -
Erratum to: Unity in defence: honeybee workers exhibit conserved molecular responses to diverse pathogens
(2017-03-23)Erratum After the publication of this work [1] it was noticed that there was a typesetting error in figure 5 where two add- itional red lines were added in the sections “gene expres- sion profiles” and “transformed gene ... -
The errors of individualistic public health interventions: Denial of treatment to obese persons: Comment on “Denial of treatment to obese patients—the wrong policy on personal responsibility for health”
(2013-09-28)I agree entirely with Nir Eyal’s perspective that denying treatment to obese patients is morally wrong. However, the reasons for this belief differ in some ways from Eyal’s analysis. In this commentary, I will try to explain ... -
Erythropoietin ameliorates chemotherapy-induced toxicity in vivo
(2002-10-17)A method of reducing organ toxicity in a subject being administered a cytotoxic agent comprising concurrently administering with the cytotoxic agent erythropoietin (EPO), the EPO being administered in an amount effective ... -
Esophageal perforation secondary to malignant gastric outlet obstruction: a case report
(2019-02-19)Background Esophageal perforation is a rare presenting sign of gastric cancer. To date, only nine case reports of this phenomenon have been previously published. Case presentation Esophageal perforation was diagnosed ... -
ESPACIO SANO: HOW SOCIAL JUSTICE EDUCATIONAL LEADERS CULTIVATE CARING AND SHARING
(East Carolina University, 2021-05-04)Healthy equitable schools need healthy social justice leaders. The study is the story of how we innovated structures and pedagogies to better support educational leaders who actively work for equity, excellence, and social ... -
Essential role of proteasomes in maintaining self-renewal in neural progenitor cells
(2016-01)Protein turnover and homeostasis are regulated by the proteasomal system, which is critical for cell function and viability. Pluripotency of stem cells also relies on normal proteasomal activity that mitigates senescent ... -
Essential role of proteasomes in maintaining self-renewal in neural progenitor cells
(2016-01-25)Protein turnover and homeostasis are regulated by the proteasomal system, which is critical for cell function and viability. Pluripotency of stem cells also relies on normal proteasomal activity that mitigates senescent ... -
Essential Role of the Iron-Regulated Outer Membrane Receptor FauA in Alcaligin Siderophore-Mediated Iron Uptake in Bordetella Species
(East Carolina University, 1999-10)Phenotypic analysis using heterologous host systems localized putative Bordetella pertussis ferric alcaligin transport genes and Fur-binding sequences to a 3.8-kb genetic region downstream from the alcR regulator gene. ... -
Establishing a Competency Protocol to Improve Pediatric Hospice Care in North Carolina
(2017-04-19)The loss of a child can have overwhelming effects on families and caregivers. End of life care focuses on providing quality health care to both the child and family. Nurses are advocates that provide interventions and ...