Browsing by Title
Now showing items 3336-3355 of 6589
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Insulin Stimulated Lactate Production
(2014)It has been shown that Type 2 diabetic patients who undergo Roux-en-Y Gastric Bypass surgery (RYGB) show a decrease in muscle lactate production, liver glucose production and pancreatic insulin secretion. To explain these ... -
Insulin-like growth factor I binding in hepatocytes from human liver, human hepatoma, and normal, regenerating, and fetal rat liver.
(East Carolina University, 1988-04)Insulin-like growth factor-I (IGF-I) in human hepatoma cells (HEP-G2) has, in addition to its effect on cell growth, shortterm metabolic effects acting through its own receptor. We have demonstrated that normal ... -
Insulin/IGF1-PI3K-dependent nucleolar localization of a glycolytic enzyme – phosphoglycerate mutase 2, is necessary for proper structure of nucleolus and RNA synthesis
(2015-07)Phosphoglycerate mutase (PGAM), a conserved, glycolytic enzyme has been found in nucleoli of cancer cells. Here, we present evidence that accumulation of PGAM in the nucleolus is a universal phenomenon concerning not only ... -
Insulin/IGF1-PI3K-dependent nucleolar localization of a glycolytic enzyme – phosphoglycerate mutase 2, is necessary for proper structure of nucleolus and RNA synthesis
(2015)Phosphoglycerate mutase (PGAM), a conserved, glycolytic enzyme has been found in nucleoli of cancer cells. Here, we present evidence that accumulation of PGAM in the nucleolus is a universal phenomenon concerning not ... -
Intact Purine Biosynthesis Pathways Are Required for Wild-Type Virulence of Brucella abortus 2308 in the BALB/c Mouse Model
(East Carolina University, 2004-08)Brucella abortus 2308 derivatives with mini-Tn5 insertions in purE, purL, and purD display significant attenuation in the BALB/c mouse model, while isogenic mutants with mini-Tn5 insertions in pheA, trpB, and dagA display ... -
Integral Captions and Subtitles: Designing a Space for Embodied Rhetorics and Visual Access
(East Carolina University, 2017-04-28)This dissertation challenges the conventions of adding static captions to the bottom of videos and instead advocates for designing integral captions and integral subtitles that interact with bodies, sound, and other modes ... -
Integrated Hazard Risk Management (IHRM) and North Carolina State Preparedness and Resource Tracking Application (NCSPARTA)
(2011-05-18)Morgan discusses two databases; Integrated Hazard Risk Management (IHRM) and North Carolina State Preparedness and Resource Tracking Application (NCSPARTA). These two databases help provide emergency managers and the general ... -
An Integrated Method for Monitoring Material Transport in a Coupled Land-Estuary System Following a Dynamic Storm Event : The Neuse River and Estuary, NC and Hurricane Irene
(East Carolina University, 2013)Coastal aquatic environments are complex and dynamic systems that are influenced by both marine and terrestrial processes such as waves, tides, winds and freshwater discharge. Rivers are conduits that transport freshwater ... -
Integrated Primary Care : A Systematic Review of Study Design and Program Characteristics
(East Carolina University, 2012)Integrated primary care (IPC), the integration of medical and behavioral health professionals, is a viable part of the solution for the United States' fragmented health care delivery system. Over the past decade or so, ... -
Integrated transcriptome, small RNA and degradome sequencing approaches provide insights into Ascochyta blight resistance in chickpea
(2018-10-16)Ascochyta blight (AB) is one of the major biotic stresses known to limit the chickpea production worldwide. To dissect the complex mechanisms of AB resistance in chickpea, three approaches, namely, transcriptome, small RNA ... -
Integrating a QR Code Identification System for First Responders and Families Within Special Needs Communities
(2021-04-27)Individuals with impaired communication, for whatever reason, can be at risk for delayed or inadequate care from first responders in the event of an emergency. One solution to this problem is utilizing QR code identification ... -
Integrating Wiki Technology into Middle School Literature Circles
(2015-05-25)This action research study used a quasi-experimental pre/post-test design to investigate the effects of integrating technology into middle school literature circles. The intervention group used wiki technology to support ... -
Integration of the 2017 ADA Depression Screening Guidelines in the Primary Care Setting
(2018-04-24)Diabetics have a doubled risk of comorbid depression that can lead to worsening healthcare outcomes and increased mortality. The American Diabetes Association (ADA) released new depression screening guidelines in the 2017 ... -
Integrative Complexity of Coastal Resources Management: Examining Tradeoffs Between Ecosystem Protection and Resource Use
(East Carolina University, 2018-07-20)The management dilemma of use versus protection is a complex issue, and like most complex issues, it does not lend itself to a simple or simplistic solution. This dissertation research examined the connection between ... -
Integrative Health Coaching : A Phenomenology of Clients' Discoveries
(East Carolina University, 2012)The field of health coaching has experienced significant growth in response to the social and economic burden of chronic disease. Integrative health coaching (IHC) applies the principles of integrative medicine and a ... -
Integrative multi-omic analyses identify novel biomarkers for recurrent stroke in participants from the Vitamin Intervention for Stroke Prevention (VISP) clinical trial
(East Carolina University, 2019-05-01)Background: Recurrent strokes are deadlier and more disabling than primary strokes and over 185,000 individuals in the US suffer a recurrent event each year. Current diagnostic and at-risk identification tools are inadequate ... -
Intellectual Treasure Hunting: Measuring Effects of Treasure Salvors on Spanish Colonial Shipwreck Sites
(East Carolina University, 1/13/16)This thesis examines the impacts of treasure salvors and looters on the Pillar Dollar Wreck (site # BISC00035) in Biscayne Bay, Florida, and explores three comparative shipwrecks from the 1733 fleet, El Populo, San Josè, ... -
INTELLIGENT MODEL FOR IMAGE-BASED RECOMMENDATION SYSTEM
(East Carolina University, 2016-08-29)Online shopping has developed in parallel with the Internet, and Recommendation Systems have played a pivotal role in its growth. The recommendations are usually provided in two ways: Content-based Filtering and Collaborative ...