Browsing by Author "Allen, William E"
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AZULENE/ALDEHYDE ASSOCIATION: AN ANALOG FOR DAMAGED DNA DETECTION
Shields, Agne A (East Carolina University, 2022-12-14)Loss of a nucleic acid base from DNA can leave behind a reactive aldehyde group on ribose. To detect the presence of such “abasic sites,” ethyl-2-aminoazulene-1-carboxylate, a novel azulene-based analog of guanine/adenine, ... -
Investigation of Platinum-Catalyzed Acylation of 2-Aryloxypyridines via C-H Activation and Functionalization
Barham, Alex Meacham (East Carolina University, 2022-07-12)Transition metal catalyzed C-H activation and functionalization reactions allow synthetic chemists to break the normally unreactive carbon-hydrogen bond and create a new and useful carbon-oxygen, carbon-nitrogen, carbon-halogen, ...