Browsing by Author "Francisco, Jake"
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A Smad3/FoxO3 Transcriptional Relationship in the Regulation of Vascular Growth
Francisco, Jake (East Carolina University, 2019-06-05)Cardiovascular disease (CVD) is a multi-faceted pathological condition that continually ranks as the number one cause of morbidity and mortality in the United States and worldwide. Unfortunately, despite extensive basic ... -
TGF-β1-directed Smad3 stimulates proliferation and alters morphology of rat primary vascular smooth muscle cells
Francisco, Jake (East Carolina University, 2017-05-05)With cardiovascular disease (CVD) being the leading cause of morbidity and death in the United States and worldwide (2, 28), studying the mechanisms of these pathologies is imperative. Recent studies have shown that a ...