Now showing items 1-3 of 3

  • Design and Application of an Immobilized Protein Kinase 

    Schulz, Anna (East Carolina University, 2023-04-26)
    Protein Kinase A (PKA) is a biologically important enzyme for cell regulation, often referred to as the “central kinase”. An immobilized PKA that retains native substrate specificity and activity would be a useful tool for ...
  • Investigation of Neurodegenerative Disease-related Cofilin-Actin Rod Dynamics Using a Novel Optogenetic Approach 

    Roberts, Davis Keith (East Carolina University, 2023-12-15)
    The presence of actin-cofilin rods in neurons is a common feature of a multitude of neurodegenerative diseases, including Alzheimer’s disease, Parkinson’s disease, and Huntingtin’s disease (Bamburg, et al 2010).  These ...
  • Red Blood Cell Preservation Under Austere Conditions 

    Angermeier, Tori Marena (East Carolina University, 2023-01-05)
    In the United States, the maximum approved preservation time for red blood cells under hypothermic storage conditions is 42 days when treated with an appropriate additive solution, namely AS-1. In this investigation, we ...