Now showing items 1-2 of 2

  • Alternative splicing of UCP1 by non-cell-autonomous action of PEMT 

    Johnson, Jordan M.; Verkerke, Anthony R.P.; Maschek, J. Alan; Ferrara, Patrick J.; Lin, Chien-Te; Kew, Kimberly A.; Neufer, P. Darrell; Lodhi, Irfan J.; Cox, James E.; Funai, Katsuhiko (2019-11-08)
    Phosphatidylethanolamine methyltransferase (PEMT) generates phosphatidylcholine (PC), the most abundant phospholipid in the mitochondria and an important acyl chain donor for cardiolipin (CL) biosynthesis. Mice lacking ...
  • Mitochondrial PE potentiates respiratory enzymes to amplify skeletal muscle aerobic capacity 

    Heden, Timothy D.; Johnson, Jordan M.; Ferrara, Patrick J.; Eshima, Hiroaki; Verkerke, Anthony R. P.; Wentzler, Edward J.; Siripoksup, Piyarat; Narowski, Tara M.; Coleman, Chanel B.; Lin, Chien-Te; Ryan, Terence E.; Reidy, Paul T.; Castro Brás, Lisandra E. de; Karner, Courtney M.; Burant, Charles F.; Maschek, J. Alan; Cox, James E.; Mashek, Douglas G.; Kardon, Gabrielle; Boudina, Sihem; Zeczycki, Tonya N.; Rutter, Jared; Shaikh, Saame Raza; Vance, Jean E.; Drummond, Micah J.; Neufer, P. Darrell; Funai, Katsuhiko (2019-09-11)
    Exercise capacity is a strong predictor of all-cause mortality. Skeletal muscle mitochondrial respiratory capacity, its biggest contributor, adapts robustly to changes in energy demands induced by contractile activity. ...