Browsing by Author "Van Dross, Rukiyah"
-
Apigenin prevents chemically-induced skin tumor formation and inhibits COX-2 expression and activity in SKH-1 mouse epidermis
Kiraly, Alex J. (East Carolina University, 2012)The most common type of cancer in the United States is non-melanoma skin cancer (NMSC), with an estimated two million new cases diagnosed each year. Numerous malignancies including NMSC, colon, breast, and prostate cancer ... -
Cannabinoids Modulate Neuronal Activity and Cancer by CB1 and CB2 Receptor-Independent Mechanisms
Soderstrom, Ken; Soliman, Eman; Van Dross, Rukiyah (2017-10-10)Cannabinoids include the active constituents of Cannabis or are molecules that mimic the structure and/or function of these Cannabis-derived molecules. Cannabinoids produce many of their cellular and organ system effects ... -
Damage-Associated Molecular Pattern (DAMP) Activation in Melanoma: Investigation of the Immunogenic Activity of 15-Deoxy, Δ12,14 Prostamide J2
Elhassanny, Ahmed; Escobedo, Rene; Van Dross, Rukiyah; Ladin, Daniel; Burns, Colin Sanderson (2021) -
Examining the therapeutic potential of the investigational agent, 15dPMJ2, in mismatch repair proficient colon cancer
Myers, Ariel (East Carolina University, 2022-08-15)Despite the success of immune checkpoint inhibitor (ICI) therapy in many cancers, colon cancer with low microsatellite instability (MSI-L), also known as proficient mismatch repair (pMMR), does not respond to these agents. ... -
J-series prostaglandin-ethanolamides as novel therapeutics for skin and/or oral disorders
Van Dross, Rukiyah (2017-09-08)Provided is a method of preventing and/or treating a skin disorder and/or an oral disorder including administering to a subject in need thereof an effective amount of a compound of formula (I) or a prodrug or derivative ... -
Kinin B1R Activation Induces Endoplasmic Reticulum Stress in Primary Hypothalamic Neurons
White, Acacia; Parekh, Rohan Umesh; Theobald, Drew; Pakala, Pranaya; Myers, Ariel Lynn; Van Dross, Rukiyah; Sriramula, Srinivas (2022-03-08) -
Preclinical and Clinical Assessment of Cannabinoids as Anti-Cancer Agents
Ladin, Daniel; Soliman, Eman; Griffin, LaToya; Van Dross, Rukiyah (2016-07)Cancer is the second leading cause of death in the United States with 1.7 million new cases estimated to be diagnosed in 2016. This disease remains a formidable clinical challenge and represents a substantial financial ...