Browsing by Author "Zhu, Yi"
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Random Walks on Finite Fields and Heisenberg Groups
Zhu, Yi (East Carolina University, 2011)Let H be a finite group and [mu] a probability measure on H. This data determines an invariant random walk on H beginning from the identity element. The probability distribution for the state of the random walk after n ... -
Rho GTPases as therapeutic targets in Alzheimer’s disease
Aguilar, Byron J.; Zhu, Yi; Lu, Qun (2017-12-15)The progress we have made in understanding Alzheimer’s disease (AD) pathogenesis has led to the identification of several novel pathways and potential therapeutic targets. Rho GTPases have been implicated as critical ... -
THE THERAPEUTIC EFFECT OF RHO KINASE INHIBITOR Y-27632 ON PROTECTION FROM CHEMOTHERAPY INDUCED PERIPHEAL NEUROPATHY IN MOUSE MODEL
Elliott, Zachary (East Carolina University, 2018-05-01)Chemotherapy drugs have neurotoxicity associated with treatment, which can become a dose-limiting problem when clinical presentation is severe. However, there is no effective therapy to circumvent the neurotoxicity of ... -
THE THERAPEUTIC ROLE OF RHO GTPASES IN TUMORIGENESIS AND CHEMOTHEARPY-INDUCED PERIPHERAL NEUROPATHY
Zhu, Yi (East Carolina University, 2019-07-15)With the advancement of chemotherapy drugs, the general life expectancy of cancer patients has drastically improved. However, persistent side effects, such as chemotherapy-induced peripheral neuropathy (CIPN), often severely ...