Browsing by Subject "Antigen Presentation"
Now showing items 1-3 of 3
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Mast cells and the IL-33/ST2 axis are essential determinants of carbon nanotube toxicity
(East Carolina University, 2012)The rise of nanomaterial use in a variety of applications, including biomedical imaging and drug delivery, has led to concern about the potentially hazardous impacts on human health. Mast cells are critical for innate and ... -
PI(4,5)P2 concentration at the APC side of the Immunological Synapse is Required for Effector T cell Function
(East Carolina University, 2009-05-01)Little is known about the signaling that occurs in an antigen presenting cell (APC) during contact with a T cell. Here we report the concentration of the signaling lipid, PI(4,5)P2, at the APC side of the immunological ... -
Tinigible Body Macrophages in Regulation of Germinal Center Reactions
(East Carolina University, 1998)Tingible body macrophages (TBM), long thought simply as scavengers of apoptotic lymphocytes, are located in the unique microenvironment of germinal centers in close proximity to antigen-retaining follicular dendritic cells ...